Publications

Saitou Group

2022

Original Articles

Gyobu-Motani, S., Yabuta, Y., Mizuta, K., Katou, Y., Okamoto, I., Kawasaki, M., Kitamura, A., Tsukiyama, T., Iwatani, C., Tsuchiya, H., Tsujimura, T., Yamamoto, T., Nakamura, T., & Saitou, M. (2023). Induction of fetal meiotic oocytes from embryonic stem cells in cynomolgus monkeys. Embo Journal. doi:10.15252/embj.2022112962

Imoto, Y., Nakamura, T., Escolar, E. G., Yoshiwaki, M., Kojima, Y., Yabuta, Y., Katou, Y., Yamamoto, T., Hiraoka, Y., & Saitou, M. (2022). Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis. Life Science Alliance, 5(12). doi:10.26508/lsa.202201591

Ishikura, Y., Ohta, H., Nagano, M., & Saitou, M. (2022). Optimized protocol to derive germline stem-cell-like cells from mouse pluripotent stem cells. STAR Protoc, 3(3), 101544. doi:10.1016/j.xpro.2022.101544

Mizuta, K., Katou, Y., Nakakita, B., Kishine, A., Nosaka, Y., Saito, S., Iwatani, C., Tsuchiya, H., Kawamoto, I., Nakaya, M., Tsukiyama, T., Nagano, M., Kojima, Y., Nakamura, T., Yabuta, Y., Horie, A., Mandai, M., Ohta, H., & Saitou, M. (2022). Ex vivo reconstitution of fetal oocyte development in humans and cynomolgus monkeys. Embo Journal, 41(18). doi:10.15252/embj.2022110815

Nagano, M., Hu, B., Yokobayashi, S., Yamamura, A., Umemura, F., Coradin, M., Ohta, H., Yabuta, Y., Ishikura, Y., Okamoto, I., Ikeda, H., Kawahira, N., Nosaka, Y., Shimizu, S., Kojima, Y., Mizuta, K., Kasahara, T., Imoto, Y., Meehan, K., Stocsits, R., Wutz, G., Hiraoka, Y., Murakawa, Y., Yamamoto, T., Tachibana, K., Peters, J. M., Mirny, L. A., Garcia, B. A., Majewski, J., & Saitou, M. (2022). Nucleome programming is required for the foundation of totipotency in mammalian germline development. Embo Journal, 41(13). doi:10.15252/embj.2022110600

2021

Original Papers

Kojima, Y., Yamashiro, C., Murase, Y., Yabuta, Y.,Okamoto, I., Iwatani, C., Tsuchiya, H., Nakaya, M., Tsukiyama, T., Nakamura, T., Yamamoto, T., & Saitou, M. (2021). GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program. Life Sci Alliance, 4(5). https://doi.org/10.26508/lsa.202000974

Io, S., Kabata, M., Iemura, Y., Semi, K., Morone, N., Minagawa, A., Wang, B., Okamoto, I., Nakamura, T., Kojima, Y., Iwatani, C., Tsuchiya, H., Kaswandy, B., Kondoh, E., Kaneko, S., Woltjen, K., Saitou, M., Yamamoto, T., Mandai, M., & Takashima, Y. (2021). Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. https://doi.org/10.1016/j.stem.2021.03.013

Review Articles

Nagaoka, SI, Saitou, M, & Kurimoto, K. (2021).Reconstituting oogenesis in vitro: recent progress and future prospects. Current Opinion in Endocrine and Metabolic Research.

Saitou, M. (2021). Mammalian germ cell development: from mechanism to in vitro reconstitution. Stem Cell Reports. https://doi.org/10.1016/j.stemcr.2021.01.008

2020

Original Papers

Matsumoto, S., Porter, C. J., Ogasawara, N., Iwatani, C., Tsuchiya, H., Seita, Y., Chang, Y. W., Okamoto, I., Saitou, M., Ema, M., Perkins, T. J., Stanford, W. L., & Tanaka, S. (2020). Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-63602-7

Murase, Y., Yabuta, Y., Ohta, H., Yamashiro, C., Nakamura,T., Yamamoto, T., & Saitou, M. (2020). Long-term expansion with germline potential of human primordial germ cell-like cells in vitro. Embo Journal, 39(21). https://doi.org/10.15252/embj.2020104929

Nagaoka, S. I., Nakaki, F., Miyauchi, H., Nosaka, Y.,Ohta, H., Yabuta, Y., Kurimoto, K., Hayashi, K., Nakamura, T., Yamamoto, T.,& Saitou, M. (2020). ZGLP1 is a determinant for the oogenic fate in mice. Science, 367(6482), 1089-+. https://doi.org/10.1126/science.aaw4115

Ohta, H, Yabuta, Y, Kurimoto, K, Nakamura, T, Murase, Y, Yamamoto,T, & Saitou, M. (2020). Cyclosporin A and FGF signaling supportthe proliferation/survival of mouse primordial germ cell-like cells in vitro. Biology of Reproduction. https://doi.org/10.1093/biolre/ioaa195

Sakai, Y., Nakamura, T., Okamoto, I., Gyobu-Motani, S., Ohta, H., Yabuta, Y., Tsukiyama, T., Iwatani, C., Tsuchiya, H., Ema,M., Morizane, A., Takahashi, J., Yamamoto, T., & Saitou, M. (2020). Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeys. Biology of Reproduction, 102(3), 620-638. https://doi.org/10.1093/biolre/ioz205

Yamashiro, C., Sasaki, K., Yokobayashi, S., Kojima, Y.,& Saitou, M. (2020). Generation of human oogonia from induced pluripotent stem cells in culture. Nature Protocols, 15(4), 1560-1583. https://doi.org/10.1038/s41596-020-0297-5

Matsumoto, S., Porter, C. J., Ogasawara, N., Iwatani, C.,Tsuchiya, H., Seita, Y., Chang, Y. W., Okamoto, I., Saitou, M., Ema, M., Perkins, T. J., Stanford, W. L., & Tanaka, S. (2020). Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-63602-7

2019

Original Paper

Mutzel, V., Okamoto, I., Dunkel, I., Saitou, M., Giorgetti, L., Heard, E., &Schulz, E. G. (2019). A symmetric toggle switch explains the onset of random Xinactivation in different mammals. Nature Structural & Molecular Biology, 26(5), 350-+. https://doi.org/10.1038/s41594-019-0214-1

Review Article

Kurimoto, K., & Saitou, M. (2019). Germ cell reprogramming. In R. Lehmann (Ed.), ImmortalGermline (Vol. 135, pp. 91-125).