Publications

Ogawa Group

Ahn, J. S., Kim, T., Kim, Y. K., Cho, Y. C., Cho, S., Jung, S. N., Ahn, S. Y., Jung, S. Y., Yang, D. H., Lee, J. J., Choi, S., Lee, J. Y., Shin, M. G., Yoshida, K., Ogawa, S., Kim, I. C., Zhang, Z. L., Kim, H. J., & Kim, D. D. H. (2019). Remission clone in acute myeloid leukemia shows growth advantage after chemotherapy but is distinct from leukemic clone. Experimental Hematology, 75, 26-30. https://doi.org/10.1016/j.exphem.2019.06.001

Becker, H., Greve, G., Kataoka, K., Mallm, J. P., Duque-Afonso, J., Ma, T., Niemoller, C., Pantic, M., Duyster, J., Cleary, M. L., Schuler, J., Rippe, K., Ogawa, S., & Lubbert, M. (2019). Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia. Blood advances, 3(5), 761-765. https://doi.org/10.1182/bloodadvances.2018023879

Cao-Sy, L., Obara, N., Sakamoto, T., Kato, T., Hattori, K., Sakashita, S., Nannya, Y., Ogawa, S., Harada, H., Sakata-Yanagimoto, M., Nishikii, H., & Chiba, S. (2019). Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis. International journal of hematology, 109(3), 309-318. https://doi.org/10.1007/s12185-018-02576-9

Christen, F., Hoyer, K., Yoshida, K., Hou, H. A., Waldhueter, N., Heuser, M., Hills, R. K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W. C., Blau, I. W., Tang, J. L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Lowenberg, B., Linch, D. C., Bullinger, L., Valk, P. J. M., Tien, H. F., Gale, R. E., Ogawa, S., & Damm, F. (2019). Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients. Blood, 133(10), 1140-1151. https://doi.org/10.1182/blood-2018-05-852822

Chung, E. Y., Mai, Y., Shah, U. A., Wei, Y. Q., Ishida, E., Kataoka, K., Ren, X. X., Pradhan, K., Bartholdy, B., Wei, X. L., Zou, Y. Y., Zhang, J. H., Ogawa, S., Steidl, U., Zang, X. X., Verma, A., Janakiram, M., & Ye, B. H. (2019). PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma. Clinical Cancer Research, 25(12), 3589-3601. https://doi.org/10.1158/1078-0432.ccr-18-3033

Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Chonabayashi, K., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M. A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K., & Nakao, S. (2019). Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia. Haematologica, 104(10), E447-E450. https://doi.org/10.3324/haematol.2018.210856

Frick, M., Chan, W., Arends, C. M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhauser, M., Blau, I. W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E. M., Spriewald, B. M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socie, G., Kroeger, N., Bullinger, L., Thiede, C., & Damm, F. (2019). Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation. Journal of Clinical Oncology, 37(5), 375-+. https://doi.org/10.1200/jco.2018.79.2184

Funakoshi, T., Miyamoto, S., Kakiuchi, N., Nikaido, M., Setoyama, T., Yokoyama, A., Horimatsu, T., Yamada, A., Torishima, M., Kosugi, S., Yamada, H., Sugimura, H., Haga, H., Sakai, Y., Ogawa, S., Seno, H., Muto, M., & Chiba, T. (2019). Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer. Gastric Cancer, 22(4), 892-898. https://doi.org/10.1007/s10120-018-00912-w

Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M. A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida, K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E., Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Ades, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellstrom-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tuchler, H., Greenberg, P. L., Bejar, R., & Int Working Grp, M. D. S. M. P. (2019). TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia, 33(7), 1747-1758. https://doi.org/10.1038/s41375-018-0351-2

Hoshino, A., Yang, X., Tanita, K., Yoshida, K., Ono, T., Nishida, N., Okuno, Y., Kanzaki, T., Goi, K., Fujino, H., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Morio, T., & Kanegane, H. (2019). Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1. Journal of Allergy and Clinical Immunology, 143(1), 421-+. https://doi.org/10.1016/j.jaci.2018.07.044

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronne, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M., Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K., & Ogawa, S. (2019). Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas. Leukemia, 33(7), 1687-1699. https://doi.org/10.1038/s41375-019-0380-5

Kawashima, N., Akashi, A., Nagata, Y., Kihara, R., Ishikawa, Y., Asou, N., Ohtake, S., Miyawaki, S., Sakura, T., Ozawa, Y., Usui, N., Kanamori, H., Ito, Y., Imai, K., Suehiro, Y., Kitamura, K., Sakaida, E., Takeshita, A., Suzushima, H., Naoe, T., Matsumura, I., Miyazaki, Y., Ogawa, S., Kiyoi, H., & Japan Adult Leukemia Study, G. (2019). Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study. Annals of Hematology, 98(1), 83-91. https://doi.org/10.1007/s00277-018-3492-5

Kim, S. K., Takeda, H., Takai, A., Matsumoto, T., Kakiuchi, N., Yokoyama, A., Yoshida, K., Kaido, T., Uemoto, S., Minamiguchi, S., Haga, H., Shiraishi, Y., Miyano, S., Seno, H., Ogawa, S., & Marusawa, H. (2019). Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis. Journal of Gastroenterology, 54(7), 628-640. https://doi.org/10.1007/s00535-019-01555-z

Kimura, S., Hasegawa, D., Yoshimoto, Y., Seki, M., Daida, A., Sekiguchi, M., Hirabayashi, S., Hosoya, Y., Kobayashi, M., Miyano, S., Ogawa, S., Takita, J., & Manabe, A. (2019). Duplication of ALK F1245 missense mutation due to acquired uniparental disomy associated with aggressive progression in a patient with relapsed neuroblastoma. Oncology Letters, 17(3), 3323-3329. https://doi.org/10.3892/ol.2019.9985

Kimura, S., Seki, M., Yoshida, K., Shiraishi, Y., Akiyama, M., Koh, K., Imamura, T., Manabe, A., Hayashi, Y., Kobayashi, M., Oka, A., Miyano, S., Ogawa, S., & Takita, J. (2019). NOTCH1 pathway activating mutations and clonal evolution in pediatric T-cell acute lymphoblastic leukemia. Cancer Science, 110(2), 784-794. https://doi.org/10.1111/cas.13859

Kohara, H., Utsugisawa, T., Sakamoto, C., Hirose, L., Ogawa, Y., Ogura, H., Sugawara, A., Liao, J. Y., Aoki, T., Iwasaki, T., Asai, T., Doisaki, S., Okuno, Y., Muramatsu, H., Abe, T., Kurita, R., Miyamoto, S., Sakuma, T., Shiba, M., Yamamoto, T., Ohga, S., Yoshida, K., Ogawa, S., Ito, E., Kojima, S., Kanno, H., & Tani, K. (2019). KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells. Experimental Hematology, 73, 25-37. https://doi.org/10.1016/j.exphem.2019.03.001

Kotani, S., Yoda, A., Kon, A., Kataoka, K., Ochi, Y., Shiozawa, Y., Hirsch, C., Takeda, J., Ueno, H., Yoshizato, T., Yoshida, K., Nakagawa, M. M., Nannya, Y., Kakiuchi, N., Yamauchi, T., Aoki, K., Shiraishi, Y., Miyano, S., Maeda, T., Maciejewski, J. P., Takaori-Kondo, A., Ogawa, S., & Makishima, H. (2019). Molecular pathogenesis of disease progression in MLL-rearranged AML. Leukemia, 33(3), 612-624. https://doi.org/10.1038/s41375-018-0253-3

Kubota, Y., Arakawa, Y., Sekiguchi, M., Watanabe, K., Hiwatari, M., Kishimoto, H., Nakazawa, A., Yoshida, A., Ogawa, S., Hanada, R., Oka, A., Takita, J., & Koh, K. (2019). A case of malignant rhabdoid tumor mimicking yolk sac tumor. Pediatric Blood & Cancer, 66(8). https://doi.org/10.1002/pbc.27784

Kubota, Y., Uryu, K., Ito, T., Seki, M., Kawai, T., Isobe, T., Kumagai, T., Toki, T., Yoshida, K., Suzuki, H., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Ohki, K., Kiyokawa, N., Kagawa, J., Miyano, S., Oka, A., Hayashi, Y., Ogawa, S., Terui, K., Sato, A., Hata, K., Ito, E., & Takita, J. (2019). Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome. Cancer Science, 110(10), 3358-3367. https://doi.org/10.1111/cas.14160

Labuhn, M., Perkins, K., Matzk, S., Varghese, L., Garnett, C., Papaemmanuil, E., Metzner, M., Kennedy, A., Amstislayskiy, V., Risch, T., Bhayadia, R., Samulowski, D., Hernandez, D. C., Stoilova, B., Lotchkova, V., Oppermann, U., Scheer, C., Yoshida, K., Schwarzer, A., Taub, J., Crispino, J. D., Weiss, M. J., Hayashi, A., Taga, T., Ito, E., Ogawa, S., Reinhardt, D., Yaspo, M. L., Campbell, P. J., Roberts, I., Constantinescu, S., Vyas, P., Heckl, D., & Klusmann, J. H. (2019). Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell, 36(2), 123-+. https://doi.org/10.1016/j.ccell.2019.06.007

Masaki, S., Ikeda, S., Hata, A., Shiozawa, Y., Kona, A., Ogawa, S., Suzuki, K., Hakuno, F., Takahashi, S. I., & Kataoka, N. (2019). Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00338

Mori, M., Hira, A., Yoshida, K., Muramatsu, H., Okuno, Y., Shiraishi, Y., Anmae, M., Yasuda, J., Tadaka, S., Kinoshita, K., Osumi, T., Noguchi, Y., Adachi, S., Kobayashi, R., Kawabata, H., Imai, K., Morio, T., Tamura, K., Takaori-Kondo, A., Yamamoto, M., Miyano, S., Kojima, S., Ito, E., Ogawa, S., Matsuo, K., Yabe, H., Yabe, M., & Takata, M. (2019). Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica, 104(10), 1962-1973. https://doi.org/10.3324/haematol.2018.207241

Nagao, Y., Mimura, N., Takeda, J., Yoshida, K., Shiozawa, Y., Oshima, M., Aoyama, K., Saraya, A., Koide, S., Rizq, O., Hasegawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Nishijima, D., Isshiki, Y., Kayamori, K., Kawajiri-Manako, C., Oshima-Hasegawa, N., Tsukamoto, S., Mitsukawa, S., Takeda, Y., Ohwada, C., Takeuchi, M., Iseki, T., Misawa, S., Miyano, S., Ohara, O., Yokote, K., Sakaida, E., Kuwabara, S., Sanada, M., Iwama, A., Ogawa, S., & Nakaseko, C. (2019). Genetic and transcriptional landscape of plasma cells in POEMS syndrome. Leukemia, 33(7), 1723-1735. https://doi.org/10.1038/s41375-018-0348-x

Ogawa, S. (2019). Genetics of MDS. Blood, 133(10), 1049-1059. https://doi.org/10.1182/blood-2018-10-844621

Okano, T., Imai, K., Tsujita, Y., Mitsuiki, N., Yoshida, K., Kamae, C., Honma, K., Mitsui-Sekinaka, K., Sekinaka, Y., Kato, T., Hanabusa, K., Endo, E., Takashima, T., Hiroki, H., Yeh, T. W., Tanaka, K., Nagahori, M., Tsuge, I., Bando, Y., Iwasaki, F., Shikama, Y., Inoue, M., Kimoto, T., Moriguchi, N., Yuza, Y., Kaneko, T., Suzuki, K., Matsubara, T., Maruo, Y., Kunitsu, T., Waragai, T., Sano, H., Hashimoto, Y., Tasaki, K., Suzuki, O., Shirakawa, T., Kato, M., Uchiyama, T., Ishimura, M., Tauchi, T., Yagasaki, H., Jou, S. T., Yu, H. H., Kanegane, H., Kracker, S., Durandy, A., Kojima, D., Muramatsu, H., Wada, T., Inoue, Y., Takada, H., Kojima, S., Ogawa, S., Ohara, O., Nonoyama, S., & Morio, T. (2019). Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase delta syndrome type 1. Journal of Allergy and Clinical Immunology, 143(1), 266-275. https://doi.org/10.1016/j.jaci.2018.04.032

Okuno, Y., Murata, T., Sato, Y., Muramatsu, H., Ito, Y., Watanabe, T., Okuno, T., Murakami, N., Yoshida, K., Sawada, A., Inoue, M., Kawa, K., Seto, M., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Narita, Y., Yoshida, M., Goshima, F., Kawada, J., Nishida, T., Kiyoi, H., Kato, S., Nakamura, S., Morishima, S., Yoshikawa, T., Fujiwara, S., Shimizu, N., Isobe, Y., Noguchi, M., Kikuta, A., Iwatsuki, K., Takahashi, Y., Kojima, S., Ogawa, S., & Kimura, H. (2019). Defective Epstein-Barr virus in chronic active infection and haematological malignancy. Nature Microbiology, 4(3), 404-413. https://doi.org/10.1038/s41564-018-0334-0

Ono, S., Matsuda, J., Watanabe, E., Akaike, H., Teranishi, H., Miyata, I., Otomo, T., Sadahira, Y., Mizuochi, T., Kusano, H., Kage, M., Ueno, H., Yoshida, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Hayashi, Y., Kanegane, H., & Ouchi, K. (2019). Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure. Human Genome Variation, 6. https://doi.org/10.1038/s41439-018-0035-5

Polprasert, C., Takeuchi, Y., Kakiuchi, N., Yoshida, K., Assanasen, T., Sitthi, W., Bunworasate, U., Pirunsarn, A., Wudhikarn, K., Lawasut, P., Uaprasert, N., Kongkiatkamon, S., Moonla, C., Sanada, M., Akita, N., Takeda, J., Fujii, Y., Suzuki, H., Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Rojnuckarin, P., Ogawa, S., & Makishima, H. (2019). Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma. Blood advances, 3(4), 588-595. https://doi.org/10.1182/bloodadvances.2018028340

Subramanian, K., Dierckx, T., Khouri, R., Menezes, S. M., Kagdi, H., Taylor, G. P., Farre, L., Bittencourt, A., Kataoka, K., Ogawa, S., & Van Weyenbergh, J. (2019). Decreased RORC expression and downstream signaling in HTLV-1-associated adult T-cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy? International Journal of Cancer, 144(7), 1664-1675. https://doi.org/10.1002/ijc.31922

Takashima, Y., Kawaguchi, A., Sato, R., Yoshida, K., Hayano, A., Homma, J., Fukai, J., Iwadate, Y., Kajiwara, K., Ishizawa, S., Hondoh, H., Nakano, M., Ogawa, S., Tashiro, K., & Yamanaka, R. (2019). Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL. Scientific Reports, 9. https://doi.org/10.1038/s41598-019-46473-5

Yabe, M., Koike, T., Ohtsubo, K., Imai, E., Morimoto, T., Takakura, H., Koh, K., Yoshida, K., Ogawa, S., Ito, E., Okuno, Y., Muramatsu, H., Kojima, S., Matsuo, K., Mori, M., Hira, A., Takata, M., & Yabe, H. (2019). Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Annals of Hematology, 98(2), 271-280. https://doi.org/10.1007/s00277-018-3517-0

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida, K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M., & Ogawa, S. (2019). Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature, 565(7739), 312-317. https://doi.org/10.1038/s41586-018-0811-x