Publications

Ogawa Group

2021

Original Papers

Klimkowska, M., Nannya, Y., Gran, C., Månsson, R., Douagi,I., Ogawa, S., Nahi, H., & Tobiasson, M. (2021). Absence of a commonfounder mutation in patients with cooccurring myelodysplastic syndrome andplasma cell disorder. Blood, 137(9), 1260-1263. https://doi.org/10.1182/blood.2020007555

Li, X. Y., Kim, W., Arif, M., Gao, C. X., Hober, A.,Kotol, D., Strandberg, L., Forsstrom, B., Sivertsson, A., Oksvold, P., Turkez,H., Grotli, M., Sato, Y., Kume, H., Ogawa, S., Boren, J., Nielsen, J.,Uhlen, M., Zhang, C., & Mardinoglu, A. (2021). Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers. Cancers, 13(2). https://doi.org/10.3390/cancers13020348

Mu, A., Hira, A., Niwa, A., Osawa, M., Yoshida, K., Mori,M., Okamoto, Y., Inoue, K., Kondo, K., Kanemaki, M. T., Matsuda, T., Ito, E.,Kojima, S., Nakahata, T., Ogawa, S., Tanaka, K., Matsuo, K., Saito, M.K., & Takata, M. (2021). Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. Blood,137(15), 2021-2032. https://doi.org/10.1182/blood.2020009111

Nishimura, A., Hirabayashi, S., Hasegawa, D., Yoshida, K.,Shiraishi, Y., Ashiarai, M., Hosoya, Y., Fujiwara, T., Harigae, H., Miyano, S.,Ogawa, S., & Manabe, A. (2021). Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome. Pediatr Blood Cancer, 68(2), e28799. https://doi.org/10.1002/pbc.28799

Polprasert, C., Takeuchi, Y., Makishima, H., Wudhikarn,K., Kakiuchi, N., Tangnuntachai, N., Assanasen, T., Sitthi, W., Muhamad, H.,Lawasut, P., Kongkiatkamon, S., Bunworasate, U., Izutsu, K., Shiraishi, Y.,Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Yoshida, K., &Rojnuckarin, P. (2021). Frequent mutations in HLA and related genes inextranodal NK/T cell lymphomas. Leuk Lymphoma, 62(1), 95-103. https://doi.org/10.1080/10428194.2020.1821011

Shimada, K., Yoshida, K., Suzuki, Y., Iriyama, C., Inoue,Y., Sanada, M., Kataoka, K., Yuge, M., Takagi, Y., Kusumoto, S., Masaki, Y.,Ito, T., Inagaki, Y., Okamoto, A., Kuwatsuka, Y., Nakatochi, M., Shimada, S.,Miyoshi, H., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Shiozawa, Y.,Nannya, Y., Okabe, A., Kohno, K., Atsuta, Y., Ohshima, K., Nakamura, S., Ogawa,S., Tomita, A., & Kiyoi, H. (2021). Frequent genetic alterations inimmune checkpoint-related genes in intravascular large B-cell lymphoma. Blood,137(11), 1491-1502. https://doi.org/10.1182/blood.2020007245

Yasudo, H., Ando, T., Maehara, A., Izawa, K., Tanabe, A.,Kaitani, A., Nomura, S., Seki, M., Yoshida, K., Oda, H., Okamoto, Y., Wang, H.,Kamei, A., Kojima, M., Kimura, M., Uchida, K., Nakano, N., Kaneko, J., Ebihara,N., Hasegawa, K., Shimizu, T., Takita, J., Ogawa, H., Okumura, K., Ogawa, S.,Tamura, N., & Kitaura, J. (2021). A possible association between a nucleotide-binding domain LRR-containing protein family PYD-containing protein 1 mutation and an autoinflammatory disease involving liver cirrhosis. Hepatology. https://doi.org/10.1002/hep.31818

Ishida, Y., Kakiuchi, N., Yoshida, K., Inoue, Y., Irie,H., Kataoka, T. R., Hirata, M., Funakoshi, T., Matsushita, S., Hata, H., Uchi,H., Yamamoto, Y., Fujisawa, Y., Fujimura, T., Saiki, R., Takeuchi, K.,Shiraishi, Y., Chiba, K., Tanaka, H., Otsuka, A., Miyano, S., Kabashima, K.,& Ogawa, S. (2021). Unbiased Detection of Driver Mutations in Extramammary Paget Disease. Clinical Cancer Research, 27(6), 1756-1765. https://doi.org/10.1158/1078-0432.ccr-20-3205

Boons, E., Nogueira, T. C., Dierckx, T., Menezes, S. M.,Jacquemyn, M., Tamir, S., Landesman, Y., Farre, L., Bittencourt, A., Kataoka,K., Ogawa, S., Snoeck, R., Andrei, G., Van Weyenbergh, J., & Daelemans, D. (2021). XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis. Blood Cancer Journal, 11(2). https://doi.org/10.1038/s41408-021-00409-3

Fujishima, N., Kohmaru, J., Koyota, S., Kuba, K., Saga,T., Omokawa, A., Moritoki, Y., Ueki, S., Ishida, F., Nakao, S., Matsuda, A.,Ohta, A., Tohyama, K., Yamasaki, H., Usuki, K., Nakashima, Y., Sato, S.,Miyazaki, Y., Nannya, Y., Ogawa, S., Sawada, K., Mitani, K., & Hirokawa, M. (2021). Clonal hematopoiesis in adult pure red cell aplasia. SciRep, 11(1), 2253. https://doi.org/10.1038/s41598-021-81890-5

Hosokawa, K., Mizumaki, H., Yoroidaka, T., Maruyama, H.,Imi, T., Tsuji, N., Urushihara, R., Tanabe, M., Zaimoku, Y., Nguyen, M. A. T.,Tran, D. C., Ishiyama, K., Yamazaki, H., Katagiri, T., Takamatsu, H.,Hosomichi, K., Tajima, A., Azuma, F., Ogawa, S., & Nakao, S. (2021). HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AMLin patients with acquired aplastic anemia. Blood. https://doi.org/10.1182/blood.2020010586

Kaburagi, T., Yamato, G., Shiba, N., Yoshida, K., Hara,Y., Tabuchi, K., Shiraishi, Y., Ohki, K., Sotomatsu, M., Arakawa, H., Matsuo,H., Shimada, A., Taki, T., Kiyokawa, N., Tomizawa, D., Horibe, K., Miyano, S.,Taga, T., Adachi, S., Ogawa, S., & Hayashi, Y. (2021). Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica. https://doi.org/10.3324/haematol.2020.269431

Kimura, S., Sekiguchi, M., Watanabe, K., Hiwatarai, M.,Seki, M., Yoshida, K., Isobe, T., Shiozawa, Y., Suzuki, H., Hoshino, N.,Hayashi, Y., Oka, A., Miyano, S., Ogawa, S., & Takita, J. (2021). Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism. Plos One, 16(1). https://doi.org/10.1371/journal.pone.0245526

Lundgren, S., Keränen, M. A. I., Kankainen, M., Huuhtanen,J., Walldin, G., Kerr, C. M., Clemente, M., Ebeling, F., Rajala, H., Brück, O.,Lähdesmäki, H., Hannula, S., Hannunen, T., Ellonen, P., Young, N. S., Ogawa,S., Maciejewski, J. P., Hellström-Lindberg, E., & Mustjoki, S. (2021). Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia.Leukemia. https://doi.org/10.1038/s41375-021-01231-3

Nakamura, F., Arai, H., Nannya, Y., Ichikawa, M.,Furuichi, S., Nagasawa, F., Takahashi, W., Handa, T., Nakamura, Y., Tanaka, H.,Sasaki, K., Miyano, S., Ogawa, S., & Mitani, K. Development of Philadelphia chromosome-negative acute myeloid leukemia with IDH2 and NPM1mutations in a patient with chronic myeloid leukemia who showed a major molecular response to tyrosine kinase inhibitor therapy. International Journal of Hematology. https://doi.org/10.1007/s12185-020-03074-7

Okabe, M., Morishita, T., Yasuda, T., Sakaguchi, H.,Sanada, M., Kataoka, K., Ogawa, S., Shiraishi, Y., Ichiki, T.,Kawaguchi, Y., Ohbiki, M., Matsumoto, R., Osaki, M., Goto, T., Ozawa, Y., & Miyamura, K. (2021). Targeted deep next generation sequencing identifies potential somatic and germline variants for predisposition to familial Burkitt lymphoma. Eur J Haematol. https://doi.org/10.1111/ejh.13629

Sakurai, M., Nannya, Y., Yamazaki, R., Yamaguchi, K.,Koda, Y., Abe, R., Yokoyama, K., Ogawa, S., & Mori, T. Germline RUNX1 translocation in familial platelet disorder with propensity to myeloidmalignancies. Annals of Hematology. https://doi.org/10.1007/s00277-021-04430-1

Tamamitsu, AM, Nakagama, Y, Domoto, Y, Yoshida, K, Ogawa,S, Hirono, K, Shindo, T, Ogawa, Y, Nakano, K, & Asakai, H. (2021). PoorMyocardial Compaction in a Patient with Recessive MYL2 Myopathy. International heart journal, 62(2), 445-447.

Review Article

Kakiuchi, N., & Ogawa, S. (2021). Clonalexpansion in non-cancer tissues. Nature Reviews Cancer, 21(4), 239-256. https://doi.org/10.1038/s41568-021-00335-3

2020

Original Papers

Kakiuchi, N., Yoshida, K., Uchino, M., Kihara, T., Akaki,K., Inoue, Y., Kawada, K., Nagayama, S., Yokoyama, A., Yamamoto, S., Matsuura,M., Horimatsu, T., Hirano, T., Goto, N., Takeuchi, Y., Ochi, Y., Shiozawa, Y.,Kogure, Y., Watatani, Y., Fujii, Y., Kim, S. K., Kon, A., Kataoka, K.,Yoshizato, T., Nakagawa, M. M., Yoda, A., Nanya, Y., Makishima, H., Shiraishi,Y., Chiba, K., Tanaka, H., Sanada, M., Sugihara, E., Sato, T., Maruyama, T.,Miyoshi, H., Taketo, M. M., Oishi, J., Inagaki, R., Ueda, Y., Okamoto, S.,Okajima, H., Sakai, Y., Sakurai, T., Haga, H., Hirota, S., Ikeuchi, H., Nakase,H., Marusawa, H., Chiba, T., Takeuchi, O., Miyano, S., Seno, H., & Ogawa,S. (2020). Frequent mutations that converge on the NFKBIZ pathway inulcerative colitis. Nature, 577(7789), 260-+. https://doi.org/10.1038/s41586-019-1856-1

Ochi, Y., Kon, A., Sakata, T., Nakagawa, M. M., Nakazawa,N., Kakuta, M., Kataoka, K., Koseki, H., Nakayama, M., Morishita, D., Tsuruyama,T., Saiki, R., Yoda, A., Okuda, R., Yoshizato, T., Yoshida, K., Shiozawa, Y.,Nannya, Y., Kotani, S., Kogure, Y., Kakiuchi, N., Nishimura, T., Makishima, H.,Malcovati, L., Yokoyama, A., Takeuchi, K., Sugihara, E., Sato, T. A., Sanada,M., Takaori-Kondo, A., Cazzola, M., Kengaku, M., Miyano, S., Shirahige, K.,Suzuki, H. I., & Ogawa, S. (2020). Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discovery, 10(6), 836-853. https://doi.org/10.1158/2159-8290.cd-19-0982

Dingler, F. A., Wang, M., Mu, A. F., Millington, C. L.,Oberbeck, N., Watcham, S., Pontel, L. B., Kamimae-Lanning, A. N., Langevin, F.,Nadler, C., Cordell, R. L., Monks, P. S., Yu, R., Wilson, N. K., Hira, A.,Yoshida, K., Mori, M., Okamoto, Y., Okuno, Y., Muramatsu, H., Shiraishi, Y.,Kobayashi, M., Moriguchi, T., Osumi, T., Kato, M., Miyano, S., Ito, E., Kojima,S., Yabe, H., Yabe, M., Matsuo, K., Ogawa, S., Gottgens, B., Hodskinson,M. R. G., Takata, M., & Patel, K. J. (2020). Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Molecular Cell, 80(6), 996-+. https://doi.org/10.1016/j.molcel.2020.10.012

Fukumoto, K., Sakata-Yanagimoto, M., Fujisawa, M.,Sakamoto, T., Miyoshi, H., Suehara, Y., Nguyen, T. B., Suma, S., Yanagimoto,S., Shiraishi, Y., Chiba, K., Bouska, A., Kataoka, K., Ogawa, S., Iqbal,J., Ohshima, K., & Chiba, S. (2020). VAV1 mutations contribute to development of T-cell neoplasms in mice. Blood, 136(26), 3018-3032. https://doi.org/10.1182/blood.2020006513

Inagaki-Kawata, Y., Yoshida, K., Kawaguchi-Sakita, N.,Kawashima, M., Nishimura, T., Senda, N., Shiozawa, Y., Takeuchi, Y., Inoue, Y.,Sato-Otsubo, A., Fujii, Y., Nannya, Y., Suzuki, E., Takada, M., Tanaka, H.,Shiraishi, Y., Chiba, K., Kataoka, Y., Torii, M., Yoshibayashi, H., Yamagami,K., Okamura, R., Moriguchi, Y., Kato, H., Tsuyuki, S., Yamauchi, A., Suwa, H.,Inamoto, T., Miyano, S., Ogawa, S., & Toi, M. (2020). Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants. Communications Biology, 3(1). https://doi.org/10.1038/s42003-020-01301-9

Kanamori, T., Sanada, M., Ri, M., Ueno, H., Nishijima, D.,Yasuda, T., Tachita, T., Narita, T., Kusumoto, S., Inagaki, A., Ishihara, R.,Murakami, Y., Kobayashi, N., Shiozawa, Y., Yoshida, K., Nakagawa, M. M.,Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Horibe, K.,Handa, H., Ogawa, S., & Iida, S. (2020). Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort. British Journal of Haematology, 191(5), 755-763. https://doi.org/10.1111/bjh.16720

Katagiri, S., Makishima, H., Azuma, K., Nannya, Y.,Saitoh, Y., Yoshizawa, S., Akahane, D., Fujimoto, H., Ito, Y., Velaga, R.,Umezu, T., Ohyashiki, J. H., Ogawa, S., & Ohyashiki, K. (2020). Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma. Haematologica, 105(7), E337-E339. https://doi.org/10.3324/haematol.2019.229856

Kimura, S., Seki, M., Kawai, T., Goto, H., Yoshida, K.,Isobe, T., Sekiguchi, M., Watanabe, K., Kubota, Y., Nannya, Y., Ueno, H.,Shiozawa, Y., Suzuki, H., Shiraishi, Y., Ohki, K., Kato, M., Koh, K.,Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N.,Manabe, A., Sanada, M., Mansour, M. R., Ohara, A., Horibe, K., Kobayashi, M.,Oka, A., Hayashi, Y., Miyano, S., Hata, K., Ogawa, S., & Takita, J.(2020). DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia, 34(4), 1163-1168. https://doi.org/10.1038/s41375-019-0626-2

Koyamaishi, S., Kamio, T., Kobayashi, A., Sato, T., Kudo,K., Sasaki, S., Kanezaki, R., Hasegawa, D., Muramatsu, H., Takahashi, Y.,Sasahara, Y., Hiramatsu, H., Kakuda, H., Tanaka, M., Ishimura, M., Nishi, M.,Ishiguro, A., Yabe, H., Sarashina, T., Yamamoto, M., Yuza, Y., Hyakuna, N.,Yoshida, K., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Miyano, S., Ogawa,S., Toki, T., Terui, K., & Ito, E. Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia. Bone Marrow Transplantation. https://doi.org/10.1038/s41409-020-01056-1

Kubota, Y., Seki, M., Kawai, T., Isobe, T., Yoshida, M.,Sekiguchi, M., Kimura, S., Watanabe, K., Sato-Otsubo, A., Yoshida, K., Suzuki,H., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Hiwatari, M.,Oka, A., Hayashi, Y., Miyano, S., Ogawa, S., Hata, K., Tanaka, Y., &Takita, J. (2020). Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets. Communications Biology, 3(1). https://doi.org/10.1038/s42003-020-01267-8

Li, X. Y., Turanli, B., Juszczak, K., Kim, W., Arif, M.,Sato, Y., Ogawa, S., Turkez, H., Nielsen, J., Boren, J., Uhlen, M.,Zhang, C., & Mardinoglu, A. (2020). Classification of clear cell renal cell carcinoma based on PKM alternative splicing. Heliyon, 6(2). https://doi.org/10.1016/j.heliyon.2020.e03440

Matsuo, H., Yoshida, K., Nakatani, K., Harata, Y.,Higashitani, M., Ito, Y., Kamikubo, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K.,Tanaka, H., Okada, A., Nannya, Y., Takeda, J., Ueno, H., Kiyokawa, N.,Tomizawa, D., Taga, T., Tawa, A., Miyano, S., Meggendorfer, M., Haferlach, C., Ogawa,S., & Adachi, S. (2020). Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML. Blood Advances, 4(19), 4623-4631. https://doi.org/10.1182/bloodadvances.2020002457

Mylonas, E., Yoshida, K., Frick, M., Hoyer, K., Christen,F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y.,Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C. C., Sawitzki, B., Schwarz, M.,Bullinger, L., le Coutre, P., Rose-Zerilli, M. J. J., Ogawa, S., & Damm, F. (2020). Single-cell analysis based dissection of clonality in myelofibrosis. Nature Communications, 11(1). https://doi.org/10.1038/s41467-019-13892-x

Ogura, H., Ohga, S., Aoki, T., Utsugisawa, T., Takahashi,H., Iwai, A., Watanabe, K., Okuno, Y., Yoshida, K., Ogawa, S., Miyano,S., Kojima, S., Yamamoto, T., Yamamoto-Shimojima, K., & Kanno, H. (2020). Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations. Human Genome Variation, 7(1). https://doi.org/10.1038/s41439-020-00130-w

Okano, T., Imai, K., Naruto, T., Okada, S., Yamashita, M.,Yeh, T. W., Ono, S., Tanaka, K., Okamoto, K., Tanita, K., Matsumoto, K.,Toyofuku, E., Kumaki-Matsumoto, E., Okamura, M., Ueno, H., Ogawa, S.,Ohara, O., Takagi, M., Kanegane, H., & Morio, T. (2020). Whole-Exome Sequencing-Based Approach for Germline Mutations in Patients with Inborn Errors of Immunity. Journal of Clinical Immunology, 40(5), 729-740. https://doi.org/10.1007/s10875-020-00798-3

Polprasert, C, Takeda, J, Niparuck, P, Rattanathammethee,T, Pirunsarn, A, Suksusut, A, Kobbuaklee, S, Wudhikarn, K, Lawasut, P,Kongkiatkamon, S, Chuncharunee, S, Songserm, K, Phowthongkum, P, Bunworasate,U, Nannya, Y, Yoshida, K, Makishima, H, Ogawa, S, & Rojnuckarin, P.(2020). Novel DDX41 variants in Thai patients with myeloid neoplasms. International Journal of Hematology, 111(2), 241-246. https://doi.org/10.1007/s12185-019-02770-3

Sekiguchi, M., Seki, M., Kawai, T., Yoshida, K., Yoshida,M., Isobe, T., Hoshino, N., Shirai, R., Tanaka, M., Souzaki, R., Watanabe, K.,Arakawa, Y., Nannya, Y., Suzuki, H., Fujii, Y., Kataoka, K., Shiraishi, Y.,Chiba, K., Tanaka, H., Shimamura, T., Sato, Y., Sato-Otsubo, A., Kimura, S.,Kubota, Y., Hiwatari, M., Koh, K., Hayashi, Y., Kanamori, Y., Kasahara, M.,Kohashi, K., Kato, M., Yoshioka, T., Matsumoto, K., Oka, A., Taguchi, T.,Sanada, M., Tanaka, Y., Miyano, S., Hata, K., Ogawa, S., & Takita,J. (2020). Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. Npj Precision Oncology,4(1). https://doi.org/10.1038/s41698-020-0125-y

Shrestha, R., Sakata-Yanagimoto, M., Maie, K., Oshima, M.,Ishihara, M., Suehara, Y., Fukumoto, K., Nakajima-Takagi, Y., Matsui, H., Kato,T., Muto, H., Sakamoto, T., Kusakabe, M., Nannya, Y., Makishima, H., Ueno, H.,Saiki, R., Ogawa, S., Chiba, K., Shiraishi, Y., Miyano, S., Mouly, E.,Bernard, O. A., Inaba, T., Koseki, H., Iwama, A., & Chiba, S. (2020). Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status. Blood Advances, 4(5), 845-854. https://doi.org/10.1182/bloodadvances.2019001324

Todisco, G., Creignou, M., Gall, A., Guglielmelli, P.,Rumi, E., Roncador, M., Rizzo, E., Nannya, Y., Pietra, D., Elena, C., Bono, E.,Molteni, E., Rosti, V., Catrical, S., Sarchi, M., Dimitriou, M., Ungerstedt,J., Vannucchi, A. M., Hellstrom-Lindberg, E., Ogawa, S., Cazzola, M.,& Malcovati, L. Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2(P95)-mutated neoplasms. Leukemia. https://doi.org/10.1038/s41375-020-01106-z

Ueno, H., Yoshida, K., Shiozawa, Y., Nannya, Y.,Iijima-Yamashita, Y., Kiyokawa, N., Shiraishi, Y., Chiba, K., Tanaka, H.,Isobe, T., Seki, M., Kimura, S., Makishima, H., Nakagawa, M. M., Kakiuchi, N.,Kataoka, K., Yoshizato, T., Nishijima, D., Deguchi, T., Ohki, K., Sato, A.,Takahashi, H., Hashii, Y., Tokimasa, S., Hara, J., Kosaka, Y., Kato, K.,Inukai, T., Takita, J., Imamura, T., Miyano, S., Manabe, A., Horibe, K., Ogawa,S., & Sanada, M. (2020). Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia. Blood Advances, 4(20), 5165-5173. https://doi.org/10.1182/bloodadvances.2019001307

Yasuda, T., Sanada, M., Nishijima, D., Kanamori, T.,Iijima, Y., Hattori, H., Saito, A., Miyoshi, H., Ishikawa, Y., Asou, N., Usuki,K., Hirabayashi, S., Kato, M., Ri, M., Handa, H., Ishida, T., Shibayama, H.,Abe, M., Iriyama, C., Karube, K., Nishikori, M., Ohshima, K., Kataoka, K.,Yoshida, K., Shiraishi, Y., Goto, H., Adachi, S., Kobayashi, R., Kiyoi, H.,Miyazaki, Y., Ogawa, S., Kurahashi, H., Yokoyama, H., Manabe, A., Iida,S., Tomita, A., & Horibe, K. (2020). Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study. Cancer Science, 111(9), 3367-3378. https://doi.org/10.1111/cas.14552

Bernard, E., Nannya, Y., Hasserjian, R. P., Devlin, S. M.,Tuechler, H., Medina-Martinez, J. S., Yoshizato, T., Shiozawa, Y., Saiki, R.,Malcovati, L., Levine, M. F., Arango, J. E., Zhou, Y. Y., Sole, F., Cargo, C.A., Haase, D., Creignou, M., Germing, U., Zhang, Y. M., Gundem, G., Sarian, A.,van de Loosdrecht, A. A., Jadersten, M., Tobiasson, M., Kosmider, O., Follo, M.Y., Thol, F., Pinheiro, R. F., Santini, V., Kotsianidis, I., Boultwood, J.,Santos, F. P. S., Schanz, J., Kasahara, S., Ishikawa, T., Tsurumi, H.,Takaori-Kondo, A., Kiguchi, T., Polprasert, C., Bennett, J. M., Klimek, V. M.,Savona, M. R., Belickova, M., Ganster, C., Palomo, L., Sanz, G., Ades, L.,Della Porta, M. G., Smith, A. G., Werner, Y., Patel, M., Viale, A., Vanness,K., Neuberg, D. S., Stevenson, K. E., Menghrajani, K., Bolton, K. L., Fenaux,P., Pellagatti, A., Platzbecker, U., Heuser, M., Valent, P., Chiba, S.,Miyazaki, Y., Finelli, C., Voso, M. T., Shih, L. Y., Fontenay, M., Jansen, J.H., Cervera, J., Atsuta, Y., Gattermann, N., Ebert, B. L., Bejar, R.,Greenberg, P. L., Cazzola, M., Hellstrom-Lindberg, E., Ogawa, S., & Papaemmanuil, E. (2020). Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature Medicine, 26(10), 1549-+. https://doi.org/10.1038/s41591-020-1008-z

Donovan, F. X., Solanki, A., Mori, M., Chavan, N., George,M., Kumar, C. S., Okuno, Y., Muramastsu, H., Yoshida, K., Shimamoto, A.,Takaori-Kondo, A., Yabe, H., Ogawa, S., Kojima, S., Yabe, M.,Ramanagoudr-Bhojappa, R., Smogorzewska, A., Mohan, S., Rajendran, A., Auerbach,A. D., Takata, M., Chandrasekharappa, S. C., & Vundinti, B. R. (2020). A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India. Human Mutation, 41(1), 122-128. https://doi.org/10.1002/humu.23914

Fujioka, M., Itonaga, H., Kato, T., Nannya, Y., Hashimoto,M., Kasai, S., Toriyama, E., Kamijo, R., Taguchi, M., Taniguchi, H., Sato, S.,Atogami, S., Imaizumi, Y., Hata, T., Moriuchi, Y., Ogawa, S., &Miyazaki, Y. (2020). Persistent clonal cytogenetic abnormality with del(20q)from an initial diagnosis of acute promyelocytic leukemia. International Journal of Hematology, 111(2), 311-316. https://doi.org/10.1007/s12185-019-02731-w

Gu, M. X., Zwiebel, M., Ong, S. H., Boughton, N.,Nomdedeu, J., Basheer, F., Nannya, Y., Quiros, P. M., Ogawa, S.,Cazzola, M., Rad, R., Butler, A. P., Vijayabaskar, M. S., & Vassiliou, G.S. (2020). RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing. Haematologica, 105(6), E290-E293. https://doi.org/10.3324/haematol.2019.230821

Hashimoto, M, Itonaga, H, Nannya, Y, Taniguchi, H, Fukuda,Y, Furumoto, T, Fujioka, M, Kasai, S, Taguchi, M, Sato, S, Sawayama, Y,Atogami, S, Iwasaki, K, Hata, T, Soda, H, Moriuchi, Y, Nakata, K, Ogawa, S,& Miyazaki, Y. (2020). Secondary Pulmonary Alveolar Proteinosis Following Treatment with Azacitidine for Myelodysplastic Syndrome. Internal Medicine,59(8), 1081-1086. https://doi.org/10.2169/internalmedicine.3770-19

Imataki, O., Ishida, T., Kubo, H., Uemura, M., Nanya, Y.,Kawakami, K., Ogawa, S., & Kadowaki, N. (2020). A Case of TyrosineKinase Inhibitor-Resistant Chronic Myeloid Leukemia, Chronic Phase with ASXL1 Mutation. Case Reports in Oncology, 13(1), 449-455. https://doi.org/10.1159/000506452

Jo, T., Nishikori, M., Kogure, Y., Arima, H., Sasaki, K.,Sasaki, Y., Nakagawa, T., Iwai, F., Momose, S., Shiraishi, A., Kiyonari, H.,Kagaya, N., Onuki, T., Shin-ya, K., Yoshida, M., Kataoka, K., Ogawa, S.,Iwai, K., & Takaori-Kondo, A. (2020). LUBAC accelerates B-celllymphomagenesis by conferring resistance to genotoxic stress on B cells. Blood,136(6), 684-697. https://doi.org/10.1182/blood.2019002654

Madan, V, Li, J, Zhou, SQ, Teoh, WW, Han, L, Meggendorfer,M, Malcovati, L, Cazzola, M, Ogawa, S, Haferlach, T, Yang, H, & Koeffler, HP. (2020). Distinct and convergent consequences of splice factormutations in myelodysplastic syndromes. American Journal of Hematology, 95(2),133-143. https://doi.org/10.1002/ajh.25673

Mori, M, Hira, A, Yoshida, K, Muramatsu, H, Okuno, Y,Shiraishi, Y, Anmae, M, Yasuda, J, Tadaka, S, Kinoshita, K, Osumi, T, Noguchi,Y, Adachi, S, Kobayashi, R, Kawabata, H, Imai, K, Morio, T, Tamura, K,Takaori-Kondo, A, Yamamoto, M, Miyano, S, Kojima, S, Ito, E, Ogawa, S,Matsuo, K, Yabe, H, Yabe, M, & Takata, M. (2020). Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients (vol ,104pg 1962, 2019). Haematologica, 105(4), 1166-1167. https://doi.org/10.3324/haematol.2019.245720

Nakagama, Y, Takeda, N, Ogawa, S, Takeda, H,Furutani, Y, Nakanishi, T, Sato, T, Hirata, Y, Oka, A, & Inuzuka, R.(2020). Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish. Molecular Genetics & Genomic Medicine, 8(3). https://doi.org/10.1002/mgg3.1107

Nguyen, M. A. T., Hosokawa, K., Yoroidaka, T., Maruyama,H., Espinoza, J. L., Elbadry, M. I., Mohiuddin, M., Tanabe, M., Katagiri, T.,Nakagawa, N., Chonabayashi, K., Yoshida, Y., Arima, N., Kashiwase, K., Saji,H., Ogawa, S., & Nakao, S. (2020). Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia. Immunohorizons,4(7), 430-441. https://doi.org/10.4049/immunohorizons.2000046

Nguyen, T. B., Sakata-Yanagimoto, M., Fujisawa, M., Nuhat,S. T., Miyoshi, H., Nannya, Y., Hashimoto, K., Fukumoto, K., Bernard, O. A.,Kiyoki, Y., Ishitsuka, K., Momose, H., Sukegawa, S., Shinagawa, A., Suyama, T.,Sato, Y., Nishikii, H., Obara, N., Kusakabe, M., Yanagimoto, S., Ogawa, S.,Ohshima, K., & Chiba, S. (2020). Dasatinib Is an Effective Treatment forAngioimmunoblastic T-cell Lymphoma. Cancer Research, 80(9), 1875-1884. https://doi.org/10.1158/0008-5472.can-19-2787

Secardin, L., Limia, C. E. G., di Stefano, A., Bonamino,M. H., Saliba, J., Kataoka, K., Rehen, S. K., Raslova, H., Marty, C., Ogawa,S., Vainchenker, W., Monte-Mor, B. D. R., & Ploa, I. (2020). TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells. Stem Cell Research, 44. https://doi.org/10.1016/j.scr.2020.101755

Shirai, R., Osumi, T., Terashima, K., Kiyotani, C.,Uchiyama, M., Tsujimoto, S., Yoshida, M., Yoshida, K., Uchiyama, T., Tomizawa,D., Shioda, Y., Sekiguchi, M., Watanabe, K., Keino, D., Ueno-Yokohata, H.,Ohki, K., Takita, J., Ito, S., Deguchi, T., Kiyokawa, N., Ogiwara, H., Hishiki,T., Ogawa, S., Okita, H., Matsumoto, K., Yoshioka, T., & Kato, M.(2020). High prevalence of SMARCB1 constitutional abnormalities including mosaicism in malignant rhabdoid tumors. European Journal of Human Genetics,28(8), 1124-1128. https://doi.org/10.1038/s41431-020-0614-z

Taguchi, M., Mishima, H., Shiozawa, Y., Hayashida, C.,Kinoshita, A., Nannya, Y., Makishima, H., Horai, M., Matsuo, M., Sato, S.,Itonaga, H., Kato, T., Taniguchi, H., Imanishi, D., Imaizumi, Y., Hata, T.,Takenaka, M., Moriuchi, Y., Shiraishi, Y., Miyano, S., Ogawa, S.,Yoshiura, K. I., & Miyazaki, Y. (2020). Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki. Haematologica, 105(2),358-365. https://doi.org/10.3324/haematol.2019.219386

Review Articles

Ogawa, S. (2020). Genetic basis of myelodysplastic syndromes. Proceedings of the Japan Academy Series B – Physical and Biological Sciences, 96(3), 107-121. https://doi.org/10.2183/pjab.96.009

Malcovati, L., Stevenson, K., Papaemmanuil, E., Neuberg,D., Bejar, R., Boultwood, J., Bowen, D. T., Campbell, P. J., Ebert, B. L.,Fenaux, P., Haferlach, T., Heuser, M., Jansen, J. H., Komrokji, R. S., Maciejewski,J. P., Walter, M. J., Fontenay, M., Garcia-Manero, G., Graubert, T. A., Karsan,A., Meggendorfer, M., Pellagatti, A., Sallman, D. A., Savona, M. R., Sekeres,M. A., Steensma, D. P., Tauro, S., Thol, F., Vyas, P., Van de Loosdrecht, A.A., Haase, D., Tuchler, H., Greenberg, P. L., Ogawa, S.,Hellstrom-Lindberg, E., & Cazzola, M. (2020). SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS. Blood, 136(2), 157-170. https://doi.org/10.1182/blood.2020004850

2019

Original Papers

Berger, G., Gerritsen, M., Yi, G. Q., Koorenhof-Scheele, T. N., Kroeze, L. I., Stevens-Kroef, M., Yoshida, K., Shiraishi, Y., van den Berg, E., Schepers, H., Huls, G., Mulder, A. B., Ogawa, S., Martens, J. H. A., Jansen, J. H., &Vellenga, E. (2019). Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern. Blood Advances, 3(20), 3111-3122. https://doi.org/10.1182/bloodadvances.2019000518

Shiba, N., Yoshida, K., Hara, Y., Yamato, G., Shiraishi, Y., Matsuo, H., Okuno, Y., Chiba, K., Tanaka, H., Kaburagi, T., Takeuchi, M., Ohki, K., Sanada, M., Okubo, J., Tomizawa, D., Taki, T., Shimada, A., Sotomatsu, M., Horibe, K., Taga, T., Adachi, S., Tawa, A., Miyano, S., Ogawa, S., & Hayashi, Y. (2019). Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia. Blood Advances, 3(20), 3157-3169. https://doi.org/10.1182/bloodadvances.2019000404

Adachi, M, Yoshida, K, Shiraishi, Y, Chiba, K, Miyano, S, & Ogawa, S. (2019). Successful treatment of pure red cell aplasia with cyclosporin in a patientwith T-cell large granular lymphocytic leukemia harboring the STAT3 D661Vmutation. [Rinsho ketsueki] The Japanese journal of clinical hematology, 60(1), 39-45. https://doi.org/10.11406/rinketsu.60.39

Ahn, J.S., Kim, T., Kim, Y. K., Cho, Y. C., Cho, S., Jung, S. N., Ahn, S. Y., Jung, S.Y., Yang, D. H., Lee, J. J., Choi, S., Lee, J. Y., Shin, M. G., Yoshida, K., Ogawa, S., Kim, I. C., Zhang, Z. L., Kim, H. J., & Kim, D. D. H. (2019). Remission clone in acute myeloid leukemia shows growth advantage after chemotherapy butis distinct from leukemic clone. Experimental Hematology, 75, 26-30. https://doi.org/10.1016/j.exphem.2019.06.001

Becker, H., Greve, G., Kataoka, K., Mallm, J. P., Duque-Afonso, J., Ma, T., Niemoller, C., Pantic, M., Duyster, J., Cleary, M. L., Schuler, J., Rippe, K., Ogawa, S., & Lubbert, M. (2019). Identification of enhancer of mRNA decapping 4 as anovel fusion partner of MLL in acute myeloid leukemia. Blood Advances, 3(5), 761-765. https://doi.org/10.1182/bloodadvances.2018023879

Cao-Sy, L., Obara, N., Sakamoto, T., Kato, T., Hattori, K., Sakashita, S., Nannya, Y., Ogawa, S., Harada, H., Sakata-Yanagimoto, M., Nishikii, H., & Chiba, S. (2019). Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis. International Journal ofHematology, 109(3), 309-318. https://doi.org/10.1007/s12185-018-02576-9

Chonabayashi, K., Yoshida, Y., Kitawaki, T., Nannya, Y., Nakamura, M., Oshima, S., Hishizawa, M., Yamashita, K., Ogawa, S., & Takaori-Kondo, A. (2019). Acute myeloidleukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dosemethotrexate therapy for rheumatoid arthritis. Annals of Hematology, 98(12), 2841-2843. https://doi.org/10.1007/s00277-019-03838-0

Christen, F., Hoyer, K., Yoshida, K., Hou, H. A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W. C., Blau, I. W., Tang, J. L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Lowenberg, B., Linch, D. C., Bullinger, L., Valk, P. J. M., Tien, H. F., Gale, R. E., Ogawa, S., & Damm, F. (2019). Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international studyon 331 patients. Blood, 133(10), 1140-1151. https://doi.org/10.1182/blood-2018-05-852822

Chung, E. Y., Mai, Y., Shah, U. A., Wei, Y. Q., Ishida, E., Kataoka, K., Ren, X. X., Pradhan, K., Bartholdy, B., Wei, X. L., Zou, Y. Y., Zhang, J. H., Ogawa, S., Steidl, U., Zang, X. X., Verma, A., Janakiram, M., & Ye, B. H. (2019). PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of AdultT-Cell Leukemia/Lymphoma. Clinical Cancer Research, 25(12), 3589-3601. https://doi.org/10.1158/1078-0432.ccr-18-3033

Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Chonabayashi, K., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M.A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K., & Nakao, S. (2019). Escape hematopoiesis by HLA-B5401-lacking hematopoietic stemprogenitor cells in men with acquired aplastic anemia. Haematologica, 104(10), E447-E450. https://doi.org/10.3324/haematol.2018.210856

Frick, M., Chan, W., Arends, C. M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhauser, M., Blau, I. W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E. M., Spriewald, B. M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socie, G., Kroeger, N., Bullinger, L., Thiede, C., & Damm, F. (2019). Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation. Journalof Clinical Oncology, 37(5), 375-+. https://doi.org/10.1200/jco.2018.79.2184

Funakoshi, T., Miyamoto, S., Kakiuchi, N., Nikaido, M., Setoyama, T., Yokoyama, A., Horimatsu, T., Yamada, A., Torishima, M., Kosugi, S., Yamada, H., Sugimura, H., Haga, H., Sakai, Y., Ogawa, S., Seno, H., Muto, M., & Chiba, T. (2019). Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer. GastricCancer, 22(4), 892-898. https://doi.org/10.1007/s10120-018-00912-w

Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M.A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida, K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E., Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Ades, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellstrom-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tuchler, H., Greenberg, P. L., Bejar, R., & IntWorking Grp, M. D. S. Mol Progno. (2019). TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia, 33(7), 1747-1758. https://doi.org/10.1038/s41375-018-0351-2

Hoshino, A., Yang, X., Tanita, K., Yoshida, K., Ono, T., Nishida, N., Okuno, Y., Kanzaki, T., Goi, K., Fujino, H., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Morio, T., & Kanegane, H. (2019). Modification of cellular and humoral immunity by somatically reverted T cellsin X-linked lymphoproliferative syndrome type 1. Journal of Allergy andClinical Immunology, 143(1), 421-+. https://doi.org/10.1016/j.jaci.2018.07.044

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronne, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M., Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K., & Ogawa, S. (2019). Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas. Leukemia, 33(7), 1687-1699. https://doi.org/10.1038/s41375-019-0380-5

Kawashima, N., Akashi, A., Nagata, Y., Kihara, R., Ishikawa, Y., Asou, N., Ohtake, S., Miyawaki, S., Sakura, T., Ozawa, Y., Usui, N., Kanamori, H., Ito, Y., Imai, K., Suehiro, Y., Kitamura, K., Sakaida, E., Takeshita, A., Suzushima, H., Naoe, T., Matsumura, I., Miyazaki, Y., Ogawa, S., Kiyoi, H., & Japan Adult LeukemiaStudy, Grp. (2019). Clinical significance of ASXL2 and ZBTB7A mutations andC-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study. Annals of Hematology, 98(1), 83-91. https://doi.org/10.1007/s00277-018-3492-5

Kim, S.K., Takeda, H., Takai, A., Matsumoto, T., Kakiuchi, N., Yokoyama, A., Yoshida, K., Kaido, T., Uemoto, S., Minamiguchi, S., Haga, H., Shiraishi, Y., Miyano, S., Seno, H., Ogawa, S., & Marusawa, H. (2019). Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis. Journal of Gastroenterology, 54(7), 628-640. https://doi.org/10.1007/s00535-019-01555-z

Kimura, S., Hasegawa, D., Yoshimoto, Y., Seki, M., Daida, A., Sekiguchi, M., Hirabayashi, S., Hosoya, Y., Kobayashi, M., Miyano, S., Ogawa, S., Takita, J., & Manabe, A. (2019). Duplication of ALK F1245 missense mutation due to acquired uniparental disomy associated with aggressive progression in a patient with relapsed neuroblastoma. Oncology Letters, 17(3), 3323-3329. https://doi.org/10.3892/ol.2019.9985

Kimura, S., Seki, M., Yoshida, K., Shiraishi, Y., Akiyama, M., Koh, K., Imamura, T., Manabe, A., Hayashi, Y., Kobayashi, M., Oka, A., Miyano, S., Ogawa, S., &Takita, J. (2019). NOTCH1 pathway activating mutations and clonal evolution inpediatric T-cell acute lymphoblastic leukemia. Cancer Science, 110(2), 784-794. https://doi.org/10.1111/cas.13859

Kobayashi, K., Mizuta, S., Yamane, N., Ueno, H., Yoshida, K., Kato, I., Umeda, K., Hiramatsu, H., Suehiro, M., Maihara, T., Usami, I., Shiraishi, Y., Chiba, K., Miyano, S., Adachi, S., Ogawa, S., Kiyokawa, N., & Heike, T. (2019). Paraneoplastic hypereosinophilic syndrome associated with IL3-IgH positive acute lymphoblastic leukemia. Pediatric Blood & Cancer, 66(1). https://doi.org/10.1002/pbc.27449

Kohara, H., Utsugisawa, T., Sakamoto, C., Hirose, L., Ogawa, Y., Ogura, H., Sugawara, A., Liao, J. Y., Aoki, T., Iwasaki, T., Asai, T., Doisaki, S., Okuno, Y., Muramatsu, H., Abe, T., Kurita, R., Miyamoto, S., Sakuma, T., Shiba, M., Yamamoto, T., Ohga, S., Yoshida, K., Ogawa, S., Ito, E., Kojima, S., Kanno, H., &Tani, K. (2019). KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells. Experimental Hematology, 73, 25-37. https://doi.org/10.1016/j.exphem.2019.03.001

Kotani, S., Yoda, A., Kon, A., Kataoka, K., Ochi, Y., Shiozawa, Y., Hirsch, C., Takeda, J., Ueno, H., Yoshizato, T., Yoshida, K., Nakagawa, M. M., Nannya, Y., Kakiuchi, N., Yamauchi, T., Aoki, K., Shiraishi, Y., Miyano, S., Maeda, T., Maciejewski, J. P., Takaori-Kondo, A., Ogawa, S., & Makishima, H. (2019). Molecular pathogenesis of disease progression in MLL-rearranged AML. Leukemia, 33(3), 612-624. https://doi.org/10.1038/s41375-018-0253-3

Kubota, Y., Arakawa, Y., Sekiguchi, M., Watanabe, K., Hiwatari, M., Kishimoto, H., Nakazawa, A., Yoshida, A., Ogawa, S., Hanada, R., Oka, A., Takita, J., &Koh, K. (2019). A case of malignant rhabdoid tumor mimicking yolk sac tumor. PediatricBlood & Cancer, 66(8). https://doi.org/10.1002/pbc.27784

Kubota, Y., Uryu, K., Ito, T., Seki, M., Kawai, T., Isobe, T., Kumagai, T., Toki, T., Yoshida, K., Suzuki, H., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Ohki, K., Kiyokawa, N., Kagawa, J., Miyano, S., Oka, A., Hayashi, Y., Ogawa, S., Terui, K., Sato, A., Hata, K., Ito, E., & Takita, J. (2019). Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome. Cancer Science, 110(10), 3358-3367. https://doi.org/10.1111/cas.14160

Labuhn, M., Perkins, K., Matzk, S., Varghese, L., Garnett, C., Papaemmanuil, E., Metzner, M., Kennedy, A., Amstislayskiy, V., Risch, T., Bhayadia, R., Samulowski, D., Hernandez, D. C., Stoilova, B., Lotchkova, V., Oppermann, U., Scheer, C., Yoshida, K., Schwarzer, A., Taub, J., Crispino, J. D., Weiss, M.J., Hayashi, A., Taga, T., Ito, E., Ogawa, S., Reinhardt, D., Yaspo, M. L., Campbell, P. J., Roberts, I., Constantinescu, S., Vyas, P., Heckl, D., &Klusmann, J. H. (2019). Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell, 36(2), 123-+. https://doi.org/10.1016/j.ccell.2019.06.007

Masaki, S., Ikeda, S., Hata, A., Shiozawa, Y., Kona, A., Ogawa, S., Suzuki, K., Hakuno, F., Takahashi, S. I., & Kataoka, N. (2019). Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00338

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Review Article

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