Publications

Alev Group

2022

Original Articles

Yamanaka, Y., Hamidi, S., Yoshioka-Kobayashi, K., Munira, S., Sunadome, K., Zhang, Y., Kurokawa, Y., Ericsson, R., Mieda, A., Thompson, J. L., Kerwin, J., Lisgo, S., Yamamoto, T., Moris, N., Martinez-Arias, A., Tsujimura, T., & Alev, C. Reconstituting human somitogenesis in vitro. Nature. doi:10.1038/s41586-022-05649-2

Review articles

Hamidi, S., & Alev, C. (2022). In vitro models of pre- and post-gastrulation embryonic development. Current Opinion in Genetics & Development, 77. doi:10.1016/j.gde.2022.101985

2021

Original Paper

Pretemer, Y., Kawai, S., Nagata, S., Nishio, M., Watanabe, M., Tamaki, S., Alev, C., Yamanaka, Y., Xue, J. Y., Wang, Z., Fukiage, K., Tsukanaka, M., Futami, T., Ikegawa, S., & Toguchida, J. (2021). Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias. Stem Cell Reports, 16(3), 610-625. https://doi.org/10.1016/j.stemcr.2021.01.014

Other Article

Koo, B. K., Bartfeld, S., & Alev, C. (2021). Organoids: ready for the revolution? J Mol Med (Berl), 99(4), 441-442. https://doi.org/10.1007/s00109-021-02063-5

2020

Original Papers

Matsuda, M., Yamanaka, Y., Uemura, M., Osawa, M., Saito, M. K., Nagahashi, A., Nishio, M., Guo, L., Ikegawa, S., Sakurai, S., Kihara, S., Maurissen, T. L., Nakamura, M., Matsumoto, T., Yoshitomi, H., Ikeya, M., Kawakami, N., Yamamoto, T., Woltjen, K., Ebisuya, M., Toguchida, J., & Alev, C. (2020). Recapitulating the human segmentation clock with pluripotent stem cells. Nature, 580(7801), 124-+. https://doi.org/10.1038/s41586-020-2144-9

Hamidi, S., Nakaya, Y., Nagai, H., Alev, C., Kasukawa, T., Chhabra, S., Lee, R., Niwa, H., Warmflash, A., Shibata, T., & Sheng, G. J. (2020). Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation. Development, 147(3). https://doi.org/10.1242/dev.184960

Kishimoto, K., Furukawa, K. T., Luz-Madrigal, A., Yamaoka, A., Matsuoka, C., Habu, M., Alev, C., Zorn, A. M., & Morimoto, M. (2020). Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-17969-w

Matsuda, M., Hayashi, H., Garcia-Ojalvo, J., Yoshioka-Kobayashi, K., Kageyama, R., Yamanaka, Y., Ikeya, M., Toguchida, J., Alev, C., & Ebisuya, M. (2020). Species-specific segmentation clock periods are due to differential biochemical reaction speeds. Science, 369(6510), 1450-+.

Other Article

McIntyre, B., Asahara, T., & Alev, C. (2020). Overview of Basic Mechanisms of Notch Signaling in Development and Disease. In J. Reichrath & S. Reichrath (Eds.), Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling, 2nd Edition (Vol. 1227, pp. 9-27).

2019

Original Papers

Hirasawa, T., Alev, C., & Kuratani, S. (2019). Twins at Conspicuously Different Developmental Stages in a Turtle Egg. Zoolog Sci, 6(1), 1-4. https://doi.org/10.2108/zs180107

Kawai, S., Yoshitomi, H., Sunaga, J., Alev, C., Nagata, S., Nishio, M., Hada, M., Koyama, Y., Uemura, M., Sekiguchi, K., Maekawa, H., Ikeya, M., Tamaki, S., Jin, Y., Harada, Y., Fukiage, K., Adachi, T., Matsuda, S., & Toguchida, J . (2019). In vitro bone-like nodules generated from patient-derived iPSCsrecapitulate pathological bone phenotypes. Nat Biomed Eng, 3(7), 558-570. https://doi.org/10.1038/s41551-019-0410-7

Mori, T., Takaoka, H., Yamane, J., Alev, C., & Fujibuchi, W. (2019). Novelcomputational model of gastrula morphogenesis to identify spatial discriminatorgenes by self-organizing map (SOM) clustering. Scientific Reports, 9. https://doi.org/10.1038/s41598-019-49031-1

Otomo, N., Takeda, K., Kawai, S., Kou, I., Guo, L., Osawa, M., Alev, C., Kawakami, N., Miyake, N., Matsumoto, N., Yasuhiko, Y., Kotani, T., Suzuki, T., Uno, K., Sudo, H., Inami, S., Taneichi, H., Shigematsu, H., Watanabe, K., Yonezawa, I., Sugawara, R., Taniguchi, Y., Minami, S., Kaneko, K., Nakamura, M., Matsumoto, M., Toguchida, J., & Ikegawa, S. (2019). Bi-allelic loss of functionvariants of. J Med Genet, 56(9), 622-628. https://doi.org/10.1136/jmedgenet-2018-105920

Review Article

Hamidi, S., Nakaya, Y., Nagai, H., Alev, C., Shibata, T., & Sheng, G. J. (2019). Biomechanical regulation of EMT and epithelial morphogenesis in amnioteepiblast. Physical Biology, 16(4). https://doi.org/10.1088/1478-3975/ab1048

Other Article

McIntyre, Brendan, Asahara, Takayuki, & Alev, Cantas. (2020). Overview of basicmechanisms of Notch signaling in development and disease. In Notch Signalingin Embryology and Cancer (pp. 9-27): Springer.