Publications
2022
Original Articles
Cui, G. W., Shimba, A., Jin, J. S., Ogawa, T., Muramoto, Y., Miyachi, H., Abe, S., Asahi, T., Tani-Ichi, S., Dijkstra, J. M., Iwamoto, Y., Kryukov, K., Zhu, Y. B., Takami, D., Hara, T., Kitano, S., Xu, Y., Morita, H., Zhang, M. Y., Zreka, L., Miyata, K., Kanaya, T., Okumura, S., Ito, T., Hatano, E., Takahashi, Y., Watarai, H., Oike, Y., Imanishi, T., Ohno, H., Ohteki, T., Minato, N., Kubo, M., Hollander, G. A., Ueno, H., Noda, T., Shiroguchi, K., & Ikuta, K. (2022). A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Science Immunology, 7(76). Retrieved from
Hamatani, M., Ochi, H., Kimura, K., Ashida, S., Hashi, Y., Okada, Y., Fujii, C., Kawamura, K., Mizuno, T., Ueno, H., Takahashi, R., & Kondo, T. (2022). T cells from MS Patients with High Disease Severity Are Insensitive to an Immune-Suppressive Effect of Sulfatide. Molecular Neurobiology, 59(9), 5276-5283. doi:10.1007/s12035-022-02881-9
Mikami, T., Kato, I., Wing, J. B., Ueno, H., Tasaka, K., Tanaka, K., Kubota, H., Saida, S., Umeda, K., Hiramatsu, H., Isobe, T., Hiwatari, M., Okada, A., Chiba, K., Shiraishi, Y., Tanaka, H., Miyano, S., Arakawa, Y., Oshima, K., Koh, K., Adachi, S., Iwaisako, K., Ogawa, S., Sakaguchi, S., & Takita, J. (2022). Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia. Cancer Sci, 113(1), 41-52. doi:10.1111/cas.15186
Tasaka, K., Ueno, H., Yamasaki, K., Okuno, T., Isobe, T., Kimura, S., Umeda, K., Hara, J., Ogawa, S., & Takita, J. (2022). Oncogenic FGFR1 mutation and amplification in common cellular origin in a composite tumor with neuroblastoma and pheochromocytoma. Cancer Science, 113(4), 1535-1541. doi:10.1111/cas.15260
Watanabe, K., Kimura, S., Seki, M., Isobe, T., Kubota, Y., Sekiguchi, M., Sato-Otsubo, A., Hiwatari, M., Kato, M., Oka, A., Koh, K., Sato, Y., Tanaka, H., Miyano, S., Kawai, T., Hata, K., Ueno, H., Nannya, Y., Suzuki, H., Yoshida, K., Fujii, Y., Nagae, G., Aburatani, H., Ogawa, S., & Takita, J. (2022). Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene, 41(46), 4994-5007. doi:10.1038/s41388-022-02489-2
Yasuda, T., Sanada, M., Kawazu, M., Kojima, S., Tsuzuki, S., Ueno, H., Iwamoto, E., Iijima-Yamashita, Y., Yamada, T., Kanamori, T., Nishimura, R., Kuwatsuka, Y., Takada, S., Tanaka, M., Ota, S., Dobashi, N., Yamazaki, E., Hirose, A., Murayama, T., Sumi, M., Sato, S., Tange, N., Nakamura, Y., Katsuoka, Y., Sakaida, E., Kawamata, T., Iida, H., Shiraishi, Y., Nannya, Y., Ogawa, S., Taniwaki, M., Asou, N., Hatta, Y., Kiyoi, H., Matsumura, I., Horibe, K., Mano, H., Naoe, T., Miyazaki, Y., & Hayakawa, F. (2022). Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations. Blood, 139(12), 1850-1862. doi:10.1182/blood.2021011921
Review articles
Yasutomi, M., Christiaansen, A. F., Imai, N., Martin-Orozco, N., Forst, C. V., Chen, G., & Ueno, H. (2022). CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.840457
Iwamoto, Y., & Ueno, H. (2022). Circulating T Follicular Helper Subsets in Human Blood. Methods Mol Biol, 2380, 29-39. doi:10.1007/978-1-0716-1736-6_3
2021
Original Papers
Ashida, S., Ochi, H., Hamatani, M., Fujii, C., Kimura, K.,Okada, Y., Hashi, Y., Kawamura, K., Ueno, H., Takahashi, R., Mizuno, T., & Kondo, T. (2021). Immune Skew of Circulating Follicular Helper T Cells Associates With Myasthenia Gravis Severity. Neurol Neuroimmunol Neuroinflamm, 8(2). https://doi.org/10.1212/NXI.0000000000000945
Tomizawa, T, Nishitani, K, Ito, H, Okae, Y, Morita, Y,Doi, K, Saito, M, Ishie, S, Yoshida, S, Murata, K, Yoshitomi, H, Kuroda, Y,& Matsuda, S. (2021). The limitations of mono‐and combination antibiotictherapies on immature biofilms in a murine model of implant‐associatedosteomyelitis. Journal of Orthopaedic Research, 39(2), 449-457.
Yamashita, A., Yoshitomi, H., Kihara, S.,Toguchida, J., & Tsumaki, N. (2021). Culture substrate-associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells. Stem Cells Transl Med, 10(1), 115-127. https://doi.org/10.1002/sctm.20-0058
Wu, J., Cheng, H., Wang, H. L., Zang, G. X., Qi, L. L.,Lv, X. P., Liu, C. Y., Zhu, S., Zhang, M. Y., Cui, J. W., Ueno, H., Liu,Y. J., Suo, J., & Chen, J. T. (2021). Correlation Between Immune Lymphoid Cells and Plasmacytoid Dendritic Cells in Human Colon Cancer. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.601611
Review Article
Yoshitomi, H., & Ueno, H. (2021). Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases. Cellular & Molecular Immunology, 18(3), 523-527. https://doi.org/10.1038/s41423-020-00529-z
2020
Original Papers
Matsuda, M., Yamanaka, Y., Uemura, M., Osawa, M., Saito,M. K., Nagahashi, A., Nishio, M., Guo, L., Ikegawa, S., Sakurai, S., Kihara,S., Maurissen, T. L., Nakamura, M., Matsumoto, T., Yoshitomi, H., Ikeya, M.,Kawakami, N., Yamamoto, T., Woltjen, K., Ebisuya, M., Toguchida, J., & Alev, C. (2020). Recapitulating the human segmentation clock with pluripotent stem cells. Nature, 580(7801), 124-+. https://doi.org/10.1038/s41586-020-2144-9
Maekawa, H., Kawai, S., Nishio, M., Nagata, S., Jin, Y., Yoshitomi,H., Matsuda, S., & Toguchida, J. (2020). Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1. Orphanet J Rare Dis, 15(1),122. https://doi.org/10.1186/s13023-020-01406-8
Okahata, A., Ito, H., Furu, M., Ishikawa, M., Fujii, T.,Hashimoto, M., Tanaka, M., Morita, Y., Azukizawa, M., Tomizawa, T., Doi, K.,Nishitani, K., Murata, K., Yoshitomi, H., Mimori, T., & Matsuda, S.(2020). Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor 1 Predicts the Changes of Rheumatoid Factor Titers in Rheumatoid Arthritis. J Clin Rheumatol, 26(7), 295-300. https://doi.org/10.1097/RHU.0000000000001116
Review Articles
Ueno, H. (2020). The IL-12-STAT4 axis in the pathogenesis of human systemic lupus erythematosus. Eur J Immunol, 50(1),10-16. https://doi.org/10.1002/eji.201948134
Yoshitomi, H. (2020). CXCL13-producing PD-1hiCXCR5− helper T cells in chronic inflammation. Immunol Med, 43(4), 156-160. https://doi.org/10.1080/25785826.2020.1781998
2019
Original Papers
Wu, H.C., Witzl, A., & Ueno, H. (2019). Assessment of TCR signal strength ofantigen-specific memory CD8(+) T cells in human blood. Blood Advances, 3(14), 2153-2163. https://doi.org/10.1182/bloodadvances.2019000292
Caielli, S., Veiga, D. T., Balasubramanian, P., Athale, S., Domic, B., Murat, E., Banchereau, R., Xu, Z. H., Chandra, M., Chung, C. H., Walters, L., Baisch, J., Wright, T., Punaro, M., Nassi, L., Stewart, K., Fuller, J., Ucar, D., Ueno, H., Zhou, J., Banchereau, J., & Pascual, V. (2019). A CD4(+) T cell populationexpanded in lupus blood provides B cell help through interleukin-10 andsuccinate. Nature Medicine, 25(1), 75-+. https://doi.org/10.1038/s41591-018-0254-9
Kawai, S., Yoshitomi, H., Sunaga, J., Alev, C., Nagata, S., Nishio, M., Hada, M., Koyama, Y., Uemura, M., Sekiguchi, K., Maekawa, H., Ikeya, M., Tamaki, S., Jin, Y., Harada, Y., Fukiage, K., Adachi, T., Matsuda, S., & Toguchida, J . (2019). In vitro bone-like nodules generated from patient-derived iPSCsrecapitulate pathological bone phenotypes. Nat Biomed Eng, 3(7), 558-570. https://doi.org/10.1038/s41551-019-0410-7
Review Articles
Ueno, H . (2020). The IL-12-STAT4 axis in the pathogenesis of human systemic lupuserythematosus. European Journal of Immunology, 50(1), 10-16. https://doi.org/10.1002/eji.201948134
Ueno, H . (2019). Tfh cell response in influenza vaccines in humans: what is visible andwhat is invisible. Current Opinion in Immunology, 59, 9-14. https://doi.org/10.1016/j.coi.2019.02.007
Yoshitomi, H. (2019). Regulation of Immune Responses and Chronic Inflammation byFibroblast-Like Synoviocytes. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.01395