Publications
2022
Original Articles
Mori, T., Okamoto, Y., Mu, A. F., Ide, Y., Yoshimura, A., Senda, N., Inagaki-Kawata, Y., Kawashima, M., Kitao, H., Tokunaga, E., Miyoshi, Y., Ohsumi, S., Tsugawa, K., Ohta, T., Katagiri, T., Ohtsuru, S., Koike, K., Ogawa, S., Toi, M., Iwata, H., Nakamura, S., Matsuo, K., & Takata, M. (2023). Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2-mutation carriers. Cancer Medicine, 12(6), 6594-6602. doi:10.1002/cam4.5430
Watase, M., Masaki, K., Chubachi, S., Namkoong, H., Tanaka, H., Lee, H., Fukushima, T., Otake, S., Nakagawara, K., Kusumoto, T., Asakura, T., Kamata, H., I, Mutoh, Y., Suzuki, Y., Edahiro, R., Sano, H., Sato, Y., Okada, Y., Koike, R., Kitagawa, Y., Tokunaga, K., Kimura, A., Imoto, S., Miyano, S., Ogawa, S.,shii, M., Hasegawa, N., Oyamada, Y., Harada, N., Ueda, T., Ueda, S., Ishiguro, T., Arimura, K., Saito, F., Yoshiyama, T., Nakano, Y. Kanai, T., Fukunaga, K., & Japan, C.-T. F. (2023). Impact of accumulative smoking exposure and chronic obstructive pulmonary disease on COVID-19 outcomes: report based on findings from the Japan COVID-19 task force. International Journal of Infectious Diseases, 128, 121-127. doi:10.1016/j.ijid.2022.12.019
Butler-Laporte, G., Povysil, G., Kosmicki, J. A., Cirulli, E. T., Drivas, T., Furini, S., Saad, C., Schmidt, A., Olszewski, P., Korotko, U., Quinodoz, M., Celik, E., Kundu, K., Walter, K., Jung, J., Stockwell, A. D., Sloofman, L. G., Jordan, D. M., Thompson, R. C., Del Valle, D., Simons, N., Cheng, E., Sebra, R., Schadt, E. E., Kim-Schulze, S., Gnjatic, S., Merad, M., Buxbaum, J. D., Beckmann, N. D., Charney, A. W., Przychodzen, B., Chang, T., Pottinger, T. D., Shang, N., Brand, F., Fava, F., Mari, F., Chwialkowska, K., Niemira, M., Pula, S., Baillie, J. K., Stuckey, A., Salas, A., Bello, X., Pardo-Seco, J., Gomez-Carballa, A., Rivero-Calle, I., Martinon-Torres, F., Ganna, A., Karczewski, K. J., Veerapen, K., Bourgey, M., Bourque, G., Eveleigh, R. J., Forgetta, V., Morrison, D., Langlais, D., Lathrop, M., Mooser, V., Nakanishi, T., Frithiof, R., Hultstrom, M., Lipcsey, M., Marincevic-Zuniga, Y., Nordlund, J., Barrett, K. M. S., Lee, W., Bolze, A., White, S., Riffle, S., Tanudjaja, F., Sandoval, E., Neveux, I., Dabe, S., Casadei, N., Motameny, S., Alaamery, M., Massadeh, S., Aljawini, N., Almutairi, M. S., Arabi, Y. M., Alqahtani, S. A., Al Harthi, F. S., Almutairi, A., Alqubaishi, F., Alotaibi, S., Binowayn, A., Alsolm, E. A., El Bardisy, H., Fawzy, M., Cai, F., Soranzo, N., Butterworth, A., Geschwind, D. H., Arteaga, S., Stephens, A., Butte, M. J., Boutros, P. C., Yamaguchi, T. N., Tao, S., Eng, S., Sanders, T., Tung, P. J., Broudy, M. E., Pan, Y., Gonzalez, A., Chavan, N., Johnson, R., Pasaniuc, B., Yaspan, B., Smieszek, S., Rivolta, C., Bibert, S., Bochud, P. Y., Dabrowski, M., Zawadzki, P., Sypniewski, M., Kaja, E., Chariyavilaskul, P., Nilaratanakul, V., Hirankarn, N., Shotelersuk, V., Pongpanich, M., Phokaew, C., Chetruengchai, W., Tokunaga, K., Sugiyama, M., Kawai, Y., Hasegawa, T., Naito, T., Namkoong, H., Edahiro, R., Kimura, A., Ogawa, S., Kanai, T., Fukunaga, K., Okada, Y., Imoto, S., Miyano, S., Mangul, S., Abedalthagafi, M. S., Zeberg, H., Grzymski, J. J., Washington, N. L., Ossowski, S., Ludwig, K. U., Schulte, E. C., Riess, O., Moniuszko, M., Kwasniewski, M., Mbarek, H., Ismail, S. I., Verma, A., Goldstein, D. B., Kiryluk, K., Renieri, A., Ferreira, M. A. R., Richards, J. B., Initiative, C.-H. G., De, C. O. I. H. G. G., Study, G.-C. M., Mt Sinai Clinical Intelligence, C., Consortium, G.-C., Gen, O. C., Japan, C.-T. F., & Regeneron Genetics, C. (2022). Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. Plos Genetics, 18(11). doi:10.1371/journal.pgen.1010367
Guzzi, N., Muthukumar, S., Ciesla, M., Todisco, G., Ngoc, P. C. T., Madej, M., Munita, R., Fazio, S., Ekstrom, S., Mortera-Blanco, T., Jansson, M., Nannya, Y., Cazzola, M., Ogawa, S., Malcovati, L., Hellstrom-Lindberg, E., Dimitriou, M., & Bellodi, C. (2022). Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome. Nature Cell Biology, 24(3), 299-+. doi:10.1038/s41556-022-00852-9
Kato, H., Maezawa, Y., Nishijima, D., Iwamoto, E., Takeda, J., Kanamori, T., Yamaga, M., Mishina, T., Takeda, Y., Izumi, S., Hino, Y., Nishi, H., Ishiko, J., Takeuchi, M., Kaneko, H., Koshizaka, M., Mimura, N., Kuzuya, M., Sakaida, E., Takemoto, M., Shiraishi, Y., Miyano, S., Ogawa, S., Iwama, A., Sanada, M., & Yokote, K. (2022). A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency. Experimental Hematology, 109, 11-17. doi:10.1016/j.exphem.2022.02.005
Li, X. Y., Shong, K., Kim, W., Yuan, M., Yang, H., Sato, Y., Kume, H., Ogawa, S., Turkez, H., Shoaie, S., Boren, J., Nielsen, J., Uhlen, M., Zhang, C., & Mardinoglu, A. (2022). Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach. Ebiomedicine, 78. doi:10.1016/j.ebiom.2022.103963
Mikami, T., Kato, I., Wing, J. B., Ueno, H., Tasaka, K., Tanaka, K., Kubota, H., Saida, S., Umeda, K., Hiramatsu, H., Isobe, T., Hiwatari, M., Okada, A., Chiba, K., Shiraishi, Y., Tanaka, H., Miyano, S., Arakawa, Y., Oshima, K., Koh, K., Adachi, S., Iwaisako, K., Ogawa, S., Sakaguchi, S., & Takita, J. (2022). Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia. Cancer Sci, 113(1), 41-52. doi:10.1111/cas.15186
Morita, Y., Nannya, Y., Ichikawa, M., Hanamoto, H., Shibayama, H., Maeda, Y., Hata, T., Miyamoto, T., Kawabata, H., Takeuchi, K., Tanaka, H., Kishimoto, J., Miyano, S., Matsumura, I., Ogawa, S., Akashi, K., Kanakura, Y., & Mitani, K. (2022). ASXL1 mutations with serum EPO levels predict poor response to darbepoetin alfa in lower-risk MDS: W-JHS MDS01 trial. International Journal of Hematology, 116(5), 659-668. doi:10.1007/s12185-022-03414-9
Nakagawara, K., Chubachi, S., Namkoong, H., Tanaka, H., Lee, H., Azekawa, S., Otake, S., Fukushima, T., Morita, A., Watase, M., Sakurai, K., Kusumoto, T., Asakura, T., Masaki, K., Kamata, H., Ishii, M., Hasegawa, N., Harada, N., Ueda, T., Ueda, S., Ishiguro, T., Arimura, K., Saito, F., Yoshiyama, T., Nakano, Y., Mutoh, Y., Suzuki, Y., Edahiro, R., Murakami, K., Sato, Y., Okada, Y., Koike, R., Kitagawa, Y., Tokunaga, K., Kimura, A., Imoto, S., Miyano, S., Ogawa, S., Kanai, T., & Fukunaga, K. (2022). Impact of upper and lower respiratory symptoms on COVID-19 outcomes: a multicenter retrospective cohort study. Respiratory Research, 23(1). doi:10.1186/s12931-022-02222-3
Namkoong, H., Edahiro, R., Takano, T., Nishihara, H., Shirai, Y., Sonehara, K., Tanaka, H., Azekawa, S., Mikami, Y., Lee, H., Hasegawa, T., Okudela, K., Okuzaki, D., Motooka, D., Kanai, M., Naito, T., Yamamoto, K., Wang, Q. B. S., Saiki, R., Ishihara, R., Matsubara, Y., Hamamoto, J., Hayashi, H., Yoshimura, Y., Tachikawa, N., Yanagita, E., Hyugaji, T., Shimizu, E., Katayama, K., Kato, Y., Morita, T., Takahashi, K., Harada, N., Hiki, M., Matsushita, Y., Takagi, H., Aoki, R., Nakamura, A., Harada, S., Sasano, H., Kabata, H., Masaki, K., Kamata, H., Ikemura, S., Chubachi, S., Okamori, S., Terai, H., Morita, A., Asakura, T., Sasaki, J., Morisaki, H., Uwamino, Y., Nanki, K., Uchida, S., Uno, S., Nishimura, T., Ishiguro, T., Isono, T., Shibata, S., Matsui, Y., Hosoda, C., Takano, K., Nishida, T., Kobayashi, Y., Takaku, Y., Takayanagi, N., Ueda, S., Tada, A., Miyawaki, M., Yamamoto, M., Yoshida, E., Hayashi, R., Nagasaka, T., Arai, S., Kaneko, Y., Sasaki, K., Tagaya, E., Kawana, M., Arimura, K., Anzai, T., Ito, S., Endo, A., Uchimura, Y., Miyazaki, Y., Honda, T., Tateishi, T., Tohda, S., Ichimura, N., Sonobe, K., Sassa, C. T., Nakajima, J., Nakano, Y., Nakajima, Y., Anan, R., Arai, R., Kurihara, Y., Harada, Y., Nishio, K., Ueda, T., Azuma, M., Saito, R., Sado, T., Sato, R., Haruta, Y., Nagasaki, T., Yasui, Y., Hasegawa, Y., Mutoh, Y., Kimura, T., Sato, T., Takei, R., Hagimoto, S., Noguchi, Y., Yamano, Y., Ota, S., Nakamori, Y., Yoshiya, K., Saito, F., Yoshihara, T., Wada, D., Iwamura, H., Kanayama, S., Maruyama, S., Yoshiyama, T., Ohta, K., Kokuto, H., Ogata, H., Tanaka, Y., Arakawa, K., Shimoda, M., Osawa, T., Tateno, H., Hase, I., Yoshida, S., Suzuki, S., Kawada, M., Horinouchi, H., Mitamura, K., Hagihara, M., Ochi, J., Uchida, T., Baba, R., Arai, D., Ogura, T., Takahashi, H., Hagiwara, S., Nagao, G., Konishi, S., Nakachi, I., Murakami, K., Yamada, M., Sugiura, H., Sano, H., Matsumoto, S., Kimura, N., Ono, Y., Baba, H., Suzuki, Y., Nakayama, S., Masuzawa, K., Namba, S., Suzuki, K., Naito, Y., Liu, Y. C., Takuwa, A., Sugihara, F., Wing, J. B., Sakakibara, S., Hizawa, N., Shiroyama, T., Miyawaki, S., Kawamura, Y., Nakayama, A., Matsuo, H., Maeda, Y., Nii, T., Noda, Y., Niitsu, T., Adachi, Y., Enomoto, T., Amiya, S., Hara, R., Yamaguchi, Y., Murakami, T., Kuge, T., Matsumoto, K., Yamamoto, Y., Yoneda, M., Kishikawa, T., Yamada, S., Kawabata, S., Kijima, N., Takagaki, M., Sasa, N., Ueno, Y., Suzuki, M., Takemoto, N., Eguchi, H., Fukusumi, T., Imai, T., Fukushima, M., Kishima, H., Inohara, H., Tomono, K., Kato, K., Takahashi, M., Matsuda, F., Hirata, H., Takeda, Y., Koh, H., Manabe, T., Funatsu, Y., Ito, F., Fukui, T., Shinozuka, K., Kohashi, S., Miyazaki, M., Shoko, T., Kojima, M., Adachi, T., Ishikawa, M., Inoue, T., Hirano, T., Kobayashi, K., Takaoka, H., Watanabe, K., Miyazawa, N., Kimura, Y., Sado, R., Sugimoto, H., Kamiya, A., Kuwahara, N., Fujiwara, A., Matsunaga, T., Sato, Y., Okada, T., Hirai, Y., Kawashima, H., Narita, A., Niwa, K., Sekikawa, Y., Nishi, K., Nishitsuji, M., Tani, M., Suzuki, J., Nakatsumi, H., Kitamura, H., Hagiwara, E., Murohashi, K., Okabayashi, H., Mochimaru, T., Nukaga, S., Satomi, R., Oyamada, Y., Mori, N., Baba, T., Fukui, Y., Odate, M., Mashimo, S., Makino, Y., Yagi, K., Hashiguchi, M., Kagyo, J., Shiomi, T., Fuke, S., Saito, H., Tsuchida, T., Fujitani, S., Takita, M., Morikawa, D., Yoshida, T., Izumo, T., Inomata, M., Kuse, N., Awano, N., Tone, M., Ito, A., Nakamura, Y., Hoshino, K., Maruyama, J., Ishikura, H., Takata, T., Odani, T., Amishima, M., Hattori, T., Shichinohe, Y., Kagaya, T., Kita, T., Sakagami, S., Koshida, K., Hayashi, K., Shimizu, T., Kozu, Y., Hiranuma, H., Gon, Y., Izumi, N., Nagata, K., Ueda, K., Taki, R., Hanada, S., Kawamura, K., Ichikado, K., Nishiyama, K., Muranaka, H., Nakamura, K., Hashimoto, N., Wakahara, K., Sakamoto, K., Omote, N., Ando, A., Kodama, N., Kaneyama, Y., Maeda, S., Kuraki, T., Matsumoto, T., Yokote, K., Nakada, T. A., Abe, R., Oshima, T., Shimada, T., Harada, M., Takahashi, T., Ono, H., Sakurai, T., Shibusawa, T., Kimizuka, Y., Kawana, A., Sano, T., Watanabe, C., Suematsu, R., Sageshima, H., Yoshifuji, A., Ito, K., Takahashi, S., Ishioka, K., Nakamura, M., Masuda, M., Wakabayashi, A., Watanabe, H., Nishikawa, M., Chihara, Y., Takeuchi, M., Onoi, K., Shinozuka, J., Sueyoshi, A., Nagasaki, Y., Okamoto, M., Ishihara, S., Shimo, M., Tokunaga, Y., Kusaka, Y., Ohba, T., Isogai, S., Ogawa, A., Fukuyama, S., Eriguchi, Y., Yonekawa, A., Kan-o, K., Kanaoka, K., Ihara, S., Komuta, K., Inoue, Y., Chiba, S., Yamagata, K., Hiramatsu, Y., Kai, H., Asano, K., Oguma, T., Ito, Y., Hashimoto, S., Yamasaki, M., Kasamatsu, Y., Komase, Y., Hida, N., Tsuburai, T., Oyama, B., Takada, M., Kanda, H., Kitagawa, Y., Fukuta, T., Miyake, T., Ogura, S., Abe, S., Kono, Y., Togashi, Y., Takoi, H., Kikuchi, R., Ogawa, S., Ogata, T., Kanehiro, A., Ozaki, S., Fuchimoto, Y., Wada, S., Fujimoto, N., Terashima, M., Beppu, S., Yoshida, K., Narumoto, O., Nagai, H., Ooshima, N., Motegi, M., Umeda, A., Miyagawa, K., Shimada, H., Endo, M., Ohira, Y., Watanabe, M., Inoue, S., Igarashi, A., Sato, M., Sagara, H., Tanaka, A., Ohta, S., Shibata, Y., Tanino, Y., Nikaido, T., Minemura, H., Yamada, Y., Hashino, T., Shinoki, M., Iwagoe, H., Fujii, K., Kishi, H., Imamura, T., Yamashita, T., Yatomi, M., Maeno, T., Hayashi, S., Kuramochi, M., Kamimaki, I., Tominaga, Y., Ishii, T., Utsugi, M., Ono, A., Tanaka, T., Kashiwada, T., Fujita, K., Saito, Y., Seike, M., Matsuse, H., Kodaka, N., Nakano, C., Oshio, T., Hirouchi, T., Makino, S., Egi, M., Omae, Y., Nannya, Y., Ueno, T., Ai, M., Kumanogoh, A., Hasegawa, N., Tokunaga, K., Ishii, M., Koike, R., Kimura, A., Imoto, S., Miyano, S., Kanai, T., Fukunaga, K., & Okada, Y. (2022). DOCK2 is involved in the host genetics and biology of severe COVID-19. Nature, 609(7928), 754-+. doi:10.1038/s41586-022-05163-5
Ogasawara, T., Fujii, Y., Kakiuchi, N., Shiozawa, Y., Sakamoto, R., Ogawa, Y., Ootani, K., Ito, E., Tanaka, T., Watanabe, K., Yoshida, Y., Kimura, N., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., & Ogawa, S. (2022). Genetic Analysis of Pheochromocytoma and Paraganglioma Complicating Cyanotic Congenital Heart Disease. Journal of Clinical Endocrinology & Metabolism, 107(9), 2545-2555. doi:10.1210/clinem/dgac362
Ogawa, S. (2022). Targeting lineage plasticity overcomes chemoresistance. Cancer Cell, 40(9), 905-907. doi:10.1016/j.ccell.2022.08.020
Sagawa, R., Sakata, S., Gong, B., Seto, Y., Takemoto, A., Takagi, S., Ninomiya, H., Yanagitani, N., Nakao, M., Mun, M., Uchibori, K., Nishio, M., Miyazaki, Y., Shiraishi, Y., Ogawa, S., Kataoka, K., Fujita, N., Takeuchi, K., & Katayama, R. (2022). Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation. Jci Insight, 7(1). doi:10.1172/jci.insight.153323
Sato-Otsubo, A., Osumi, T., Yoshida, M., Iguchi, A., Fukushima, T., Nakabayashi, K., Ogawa, S., Hata, K., & Kato, M. (2022). Genomic analysis of two rare cases of pediatric Ph-positive T-ALL. Pediatr Blood Cancer, 69(3), e29427. doi:10.1002/pbc.29427
Shingaki, S., Koya, J., Yuasa, M., Saito, Y., Tabata, M., McClure, M. B., Ogawa, S., Katayama, K., Togashi, Y., Imoto, S., Kogure, Y., & Kataoka, K. Tumor-promoting function and regulatory landscape of PD-L2 in B-cell lymphoma. Leukemia. doi:10.1038/s41375-022-01772-1
Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B. M., Bullinger, L., Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S., & Damm, F. (2022). The landscape of genetic aberrations in myxofibrosarcoma. International Journal of Cancer, 151(4), 565-577. doi:10.1002/ijc.34051
Tasaka, K., Ueno, H., Yamasaki, K., Okuno, T., Isobe, T., Kimura, S., Umeda, K., Hara, J., Ogawa, S., & Takita, J. (2022). Oncogenic FGFR1 mutation and amplification in common cellular origin in a composite tumor with neuroblastoma and pheochromocytoma. Cancer Science, 113(4), 1535-1541. doi:10.1111/cas.15260
Wang, Q. B. S., Edahiro, R., Namkoong, H., Hasegawa, T., Shirai, Y., Sonehara, K., Tanaka, H., Lee, H., Saiki, R., Hyugaji, T., Shimizu, E., Katayama, K., Kanai, M., Naito, T., Sasa, N., Yamamoto, K., Kato, Y., Morita, T., Takahashi, K., Harada, N., Hiki, M., Matsushita, Y., Takagi, H., Ichikawa, M., Nakamura, A., Harada, S., Sandhu, Y., Kabata, H., Masaki, K., Kamata, H., Ikemura, S., Chubachi, S., Okamori, S., Terai, H., Morita, A., Asakura, T., Sasaki, J., Morisaki, H., Uwamino, Y., Nanki, K., Uchida, S., Uno, S., Nishimura, T., Ishiguro, T., Isono, T., Shibata, S., Matsui, Y., Hosoda, C., Takano, K., Nishida, T., Kobayashi, Y., Takaku, Y., Takayanagi, N., Ueda, S., Tada, A., Miyawaki, M., Yamamoto, M., Yoshida, E., Hayashi, R., Nagasaka, T., Arai, S., Kaneko, Y., Sasaki, K., Tagaya, E., Kawana, M., Arimura, K., Anzai, T., Ito, S., Endo, A., Uchimura, Y., Miyazaki, Y., Honda, T., Tateishi, T., Tohda, S., Ichimura, N., Sonobe, K., Sassa, C. T., Nakajima, J., Nakano, Y., Nakajima, Y., Anan, R., Arai, R., Kurihara, Y., Harada, Y., Nishio, K., Ueda, T., Azuma, M., Saito, R., Sado, T., Sato, R., Haruta, Y., Nagasaki, T., Yasui, Y., Hasegawa, Y., Mutoh, Y., Kimura, T., Sato, T., Takei, R., Hagimoto, S., Noguchi, Y., Yamano, Y., Sasano, H., Ota, S., Nakamori, Y., Yoshiya, K., Saito, F., Yoshihara, T., Wada, D., Iwamura, H., Kanayama, S., Maruyama, S., Yoshiyama, T., Ohta, K., Kokuto, H., Ogata, H., Tanaka, Y., Arakawa, K., Shimoda, M., Osawa, T., Tateno, H., Hase, I., Yoshida, S., Suzuki, S., Kawada, M., Horinouchi, H., Mitamura, K., Hagihara, M., Ochi, J., Uchida, T., Baba, R., Arai, D., Ogura, T., Takahashi, H., Hagiwara, S., Nagao, G., Konishi, S., Nakachi, I., Murakami, K., Yamada, M., Sugiura, H., Sano, H., Matsumoto, S., Kimura, N., Ono, Y., Baba, H., Suzuki, Y., Nakayama, S., Masuzawa, K., Namba, S., Shiroyama, T., Noda, Y., Niitsu, T., Adachi, Y., Enomoto, T., Amiya, S., Hara, R., Yamaguchi, Y., Murakami, T., Kuge, T., Matsumoto, K., Yamamoto, Y., Yoneda, M., Tomono, K., Kato, K., Hirata, H., Takeda, Y., Koh, H., Manabe, T., Funatsu, Y., Ito, F., Fukui, T., Shinozuka, K., Kohashi, S., Miyazaki, M., Shoko, T., Kojima, M., Adachi, T., Ishikawa, M., Inoue, T., Hirano, T., Kobayashi, K., Takaoka, H., Watanabe, K., Miyazawa, N., Kimura, Y., Sado, R., Sugimoto, H., Kamiya, A., Kuwahara, N., Fujiwara, A., Matsunaga, T., Sato, Y., Okada, T., Hirai, Y., Kawashima, H., Narita, A., Niwa, K., Sekikawa, Y., Nishi, K., Nishitsuji, M., Tani, M., Suzuki, J., Nakatsumi, H., Kitamura, H., Hagiwara, E., Murohashi, K., Okabayashi, H., Mochimaru, T., Nukaga, S., Satomi, R., Oyamada, Y., Mori, N., Baba, T., Fukui, Y., Odate, M., Mashimo, S., Makino, Y., Yagi, K., Hashiguchi, M., Kagyo, J., Shiomi, T., Fuke, S., Saito, H., Tsuchida, T., Fujitani, S., Takita, M., Morikawa, D., Yoshida, T., Izumo, T., Inomata, M., Kuse, N., Awano, N., Tone, M., Ito, A., Nakamura, Y., Hoshino, K., Maruyama, J., Ishikura, H., Takata, T., Odani, T., Amishima, M., Hattori, T., Shichinohe, Y., Kagaya, T., Kita, T., Sakagami, S., Koshida, K., Hayashi, K., Shimizu, T., Kozu, Y., Hiranuma, H., Gon, Y., Izumi, N., Nagata, K., Ueda, K., Taki, R., Hanada, S., Kawamura, K., Ichikado, K., Nishiyama, K., Muranaka, H., Nakamura, K., Hashimoto, N., Wakahara, K., Koji, S., Omote, N., Ando, A., Kodama, N., Kaneyama, Y., Maeda, S., Kuraki, T., Matsumoto, T., Yokote, K., Nakada, T. 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Watanabe, K., Kimura, S., Seki, M., Isobe, T., Kubota, Y., Sekiguchi, M., Sato-Otsubo, A., Hiwatari, M., Kato, M., Oka, A., Koh, K., Sato, Y., Tanaka, H., Miyano, S., Kawai, T., Hata, K., Ueno, H., Nannya, Y., Suzuki, H., Yoshida, K., Fujii, Y., Nagae, G., Aburatani, H., Ogawa, S., & Takita, J. (2022). Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene, 41(46), 4994-5007. doi:10.1038/s41388-022-02489-2
Yasuda, T., Sanada, M., Kawazu, M., Kojima, S., Tsuzuki, S., Ueno, H., Iwamoto, E., Iijima-Yamashita, Y., Yamada, T., Kanamori, T., Nishimura, R., Kuwatsuka, Y., Takada, S., Tanaka, M., Ota, S., Dobashi, N., Yamazaki, E., Hirose, A., Murayama, T., Sumi, M., Sato, S., Tange, N., Nakamura, Y., Katsuoka, Y., Sakaida, E., Kawamata, T., Iida, H., Shiraishi, Y., Nannya, Y., Ogawa, S., Taniwaki, M., Asou, N., Hatta, Y., Kiyoi, H., Matsumura, I., Horibe, K., Mano, H., Naoe, T., Miyazaki, Y., & Hayakawa, F. (2022). Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations. Blood, 139(12), 1850-1862. doi:10.1182/blood.2021011921
2021
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Klimkowska, M., Nannya, Y., Gran, C., Månsson, R., Douagi,I., Ogawa, S., Nahi, H., & Tobiasson, M. (2021). Absence of a commonfounder mutation in patients with cooccurring myelodysplastic syndrome andplasma cell disorder. Blood, 137(9), 1260-1263. https://doi.org/10.1182/blood.2020007555
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Mu, A., Hira, A., Niwa, A., Osawa, M., Yoshida, K., Mori,M., Okamoto, Y., Inoue, K., Kondo, K., Kanemaki, M. T., Matsuda, T., Ito, E.,Kojima, S., Nakahata, T., Ogawa, S., Tanaka, K., Matsuo, K., Saito, M.K., & Takata, M. (2021). Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. Blood,137(15), 2021-2032. https://doi.org/10.1182/blood.2020009111
Nishimura, A., Hirabayashi, S., Hasegawa, D., Yoshida, K.,Shiraishi, Y., Ashiarai, M., Hosoya, Y., Fujiwara, T., Harigae, H., Miyano, S.,Ogawa, S., & Manabe, A. (2021). Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome. Pediatr Blood Cancer, 68(2), e28799. https://doi.org/10.1002/pbc.28799
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Shimada, K., Yoshida, K., Suzuki, Y., Iriyama, C., Inoue,Y., Sanada, M., Kataoka, K., Yuge, M., Takagi, Y., Kusumoto, S., Masaki, Y.,Ito, T., Inagaki, Y., Okamoto, A., Kuwatsuka, Y., Nakatochi, M., Shimada, S.,Miyoshi, H., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Shiozawa, Y.,Nannya, Y., Okabe, A., Kohno, K., Atsuta, Y., Ohshima, K., Nakamura, S., Ogawa,S., Tomita, A., & Kiyoi, H. (2021). Frequent genetic alterations inimmune checkpoint-related genes in intravascular large B-cell lymphoma. Blood,137(11), 1491-1502. https://doi.org/10.1182/blood.2020007245
Yasudo, H., Ando, T., Maehara, A., Izawa, K., Tanabe, A.,Kaitani, A., Nomura, S., Seki, M., Yoshida, K., Oda, H., Okamoto, Y., Wang, H.,Kamei, A., Kojima, M., Kimura, M., Uchida, K., Nakano, N., Kaneko, J., Ebihara,N., Hasegawa, K., Shimizu, T., Takita, J., Ogawa, H., Okumura, K., Ogawa, S.,Tamura, N., & Kitaura, J. (2021). A possible association between a nucleotide-binding domain LRR-containing protein family PYD-containing protein 1 mutation and an autoinflammatory disease involving liver cirrhosis. Hepatology. https://doi.org/10.1002/hep.31818
Ishida, Y., Kakiuchi, N., Yoshida, K., Inoue, Y., Irie,H., Kataoka, T. R., Hirata, M., Funakoshi, T., Matsushita, S., Hata, H., Uchi,H., Yamamoto, Y., Fujisawa, Y., Fujimura, T., Saiki, R., Takeuchi, K.,Shiraishi, Y., Chiba, K., Tanaka, H., Otsuka, A., Miyano, S., Kabashima, K.,& Ogawa, S. (2021). Unbiased Detection of Driver Mutations in Extramammary Paget Disease. Clinical Cancer Research, 27(6), 1756-1765. https://doi.org/10.1158/1078-0432.ccr-20-3205
Boons, E., Nogueira, T. C., Dierckx, T., Menezes, S. M.,Jacquemyn, M., Tamir, S., Landesman, Y., Farre, L., Bittencourt, A., Kataoka,K., Ogawa, S., Snoeck, R., Andrei, G., Van Weyenbergh, J., & Daelemans, D. (2021). XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis. Blood Cancer Journal, 11(2). https://doi.org/10.1038/s41408-021-00409-3
Fujishima, N., Kohmaru, J., Koyota, S., Kuba, K., Saga,T., Omokawa, A., Moritoki, Y., Ueki, S., Ishida, F., Nakao, S., Matsuda, A.,Ohta, A., Tohyama, K., Yamasaki, H., Usuki, K., Nakashima, Y., Sato, S.,Miyazaki, Y., Nannya, Y., Ogawa, S., Sawada, K., Mitani, K., & Hirokawa, M. (2021). Clonal hematopoiesis in adult pure red cell aplasia. SciRep, 11(1), 2253. https://doi.org/10.1038/s41598-021-81890-5
Hosokawa, K., Mizumaki, H., Yoroidaka, T., Maruyama, H.,Imi, T., Tsuji, N., Urushihara, R., Tanabe, M., Zaimoku, Y., Nguyen, M. A. T.,Tran, D. C., Ishiyama, K., Yamazaki, H., Katagiri, T., Takamatsu, H.,Hosomichi, K., Tajima, A., Azuma, F., Ogawa, S., & Nakao, S. (2021). HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AMLin patients with acquired aplastic anemia. Blood. https://doi.org/10.1182/blood.2020010586
Kaburagi, T., Yamato, G., Shiba, N., Yoshida, K., Hara,Y., Tabuchi, K., Shiraishi, Y., Ohki, K., Sotomatsu, M., Arakawa, H., Matsuo,H., Shimada, A., Taki, T., Kiyokawa, N., Tomizawa, D., Horibe, K., Miyano, S.,Taga, T., Adachi, S., Ogawa, S., & Hayashi, Y. (2021). Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica. https://doi.org/10.3324/haematol.2020.269431
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Lundgren, S., Keränen, M. A. I., Kankainen, M., Huuhtanen,J., Walldin, G., Kerr, C. M., Clemente, M., Ebeling, F., Rajala, H., Brück, O.,Lähdesmäki, H., Hannula, S., Hannunen, T., Ellonen, P., Young, N. S., Ogawa,S., Maciejewski, J. P., Hellström-Lindberg, E., & Mustjoki, S. (2021). Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia.Leukemia. https://doi.org/10.1038/s41375-021-01231-3
Nakamura, F., Arai, H., Nannya, Y., Ichikawa, M.,Furuichi, S., Nagasawa, F., Takahashi, W., Handa, T., Nakamura, Y., Tanaka, H.,Sasaki, K., Miyano, S., Ogawa, S., & Mitani, K. Development of Philadelphia chromosome-negative acute myeloid leukemia with IDH2 and NPM1mutations in a patient with chronic myeloid leukemia who showed a major molecular response to tyrosine kinase inhibitor therapy. International Journal of Hematology. https://doi.org/10.1007/s12185-020-03074-7
Okabe, M., Morishita, T., Yasuda, T., Sakaguchi, H.,Sanada, M., Kataoka, K., Ogawa, S., Shiraishi, Y., Ichiki, T.,Kawaguchi, Y., Ohbiki, M., Matsumoto, R., Osaki, M., Goto, T., Ozawa, Y., & Miyamura, K. (2021). Targeted deep next generation sequencing identifies potential somatic and germline variants for predisposition to familial Burkitt lymphoma. Eur J Haematol. https://doi.org/10.1111/ejh.13629
Sakurai, M., Nannya, Y., Yamazaki, R., Yamaguchi, K.,Koda, Y., Abe, R., Yokoyama, K., Ogawa, S., & Mori, T. Germline RUNX1 translocation in familial platelet disorder with propensity to myeloidmalignancies. Annals of Hematology. https://doi.org/10.1007/s00277-021-04430-1
Tamamitsu, AM, Nakagama, Y, Domoto, Y, Yoshida, K, Ogawa,S, Hirono, K, Shindo, T, Ogawa, Y, Nakano, K, & Asakai, H. (2021). PoorMyocardial Compaction in a Patient with Recessive MYL2 Myopathy. International heart journal, 62(2), 445-447.
Review Article
Kakiuchi, N., & Ogawa, S. (2021). Clonalexpansion in non-cancer tissues. Nature Reviews Cancer, 21(4), 239-256. https://doi.org/10.1038/s41568-021-00335-3
2020
Original Papers
Kakiuchi, N., Yoshida, K., Uchino, M., Kihara, T., Akaki,K., Inoue, Y., Kawada, K., Nagayama, S., Yokoyama, A., Yamamoto, S., Matsuura,M., Horimatsu, T., Hirano, T., Goto, N., Takeuchi, Y., Ochi, Y., Shiozawa, Y.,Kogure, Y., Watatani, Y., Fujii, Y., Kim, S. K., Kon, A., Kataoka, K.,Yoshizato, T., Nakagawa, M. M., Yoda, A., Nanya, Y., Makishima, H., Shiraishi,Y., Chiba, K., Tanaka, H., Sanada, M., Sugihara, E., Sato, T., Maruyama, T.,Miyoshi, H., Taketo, M. M., Oishi, J., Inagaki, R., Ueda, Y., Okamoto, S.,Okajima, H., Sakai, Y., Sakurai, T., Haga, H., Hirota, S., Ikeuchi, H., Nakase,H., Marusawa, H., Chiba, T., Takeuchi, O., Miyano, S., Seno, H., & Ogawa,S. (2020). Frequent mutations that converge on the NFKBIZ pathway inulcerative colitis. Nature, 577(7789), 260-+. https://doi.org/10.1038/s41586-019-1856-1
Ochi, Y., Kon, A., Sakata, T., Nakagawa, M. M., Nakazawa,N., Kakuta, M., Kataoka, K., Koseki, H., Nakayama, M., Morishita, D., Tsuruyama,T., Saiki, R., Yoda, A., Okuda, R., Yoshizato, T., Yoshida, K., Shiozawa, Y.,Nannya, Y., Kotani, S., Kogure, Y., Kakiuchi, N., Nishimura, T., Makishima, H.,Malcovati, L., Yokoyama, A., Takeuchi, K., Sugihara, E., Sato, T. A., Sanada,M., Takaori-Kondo, A., Cazzola, M., Kengaku, M., Miyano, S., Shirahige, K.,Suzuki, H. I., & Ogawa, S. (2020). Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discovery, 10(6), 836-853. https://doi.org/10.1158/2159-8290.cd-19-0982
Dingler, F. A., Wang, M., Mu, A. F., Millington, C. L.,Oberbeck, N., Watcham, S., Pontel, L. B., Kamimae-Lanning, A. N., Langevin, F.,Nadler, C., Cordell, R. L., Monks, P. S., Yu, R., Wilson, N. K., Hira, A.,Yoshida, K., Mori, M., Okamoto, Y., Okuno, Y., Muramatsu, H., Shiraishi, Y.,Kobayashi, M., Moriguchi, T., Osumi, T., Kato, M., Miyano, S., Ito, E., Kojima,S., Yabe, H., Yabe, M., Matsuo, K., Ogawa, S., Gottgens, B., Hodskinson,M. R. G., Takata, M., & Patel, K. J. (2020). Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Molecular Cell, 80(6), 996-+. https://doi.org/10.1016/j.molcel.2020.10.012
Fukumoto, K., Sakata-Yanagimoto, M., Fujisawa, M.,Sakamoto, T., Miyoshi, H., Suehara, Y., Nguyen, T. B., Suma, S., Yanagimoto,S., Shiraishi, Y., Chiba, K., Bouska, A., Kataoka, K., Ogawa, S., Iqbal,J., Ohshima, K., & Chiba, S. (2020). VAV1 mutations contribute to development of T-cell neoplasms in mice. Blood, 136(26), 3018-3032. https://doi.org/10.1182/blood.2020006513
Inagaki-Kawata, Y., Yoshida, K., Kawaguchi-Sakita, N.,Kawashima, M., Nishimura, T., Senda, N., Shiozawa, Y., Takeuchi, Y., Inoue, Y.,Sato-Otsubo, A., Fujii, Y., Nannya, Y., Suzuki, E., Takada, M., Tanaka, H.,Shiraishi, Y., Chiba, K., Kataoka, Y., Torii, M., Yoshibayashi, H., Yamagami,K., Okamura, R., Moriguchi, Y., Kato, H., Tsuyuki, S., Yamauchi, A., Suwa, H.,Inamoto, T., Miyano, S., Ogawa, S., & Toi, M. (2020). Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants. Communications Biology, 3(1). https://doi.org/10.1038/s42003-020-01301-9
Kanamori, T., Sanada, M., Ri, M., Ueno, H., Nishijima, D.,Yasuda, T., Tachita, T., Narita, T., Kusumoto, S., Inagaki, A., Ishihara, R.,Murakami, Y., Kobayashi, N., Shiozawa, Y., Yoshida, K., Nakagawa, M. M.,Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Horibe, K.,Handa, H., Ogawa, S., & Iida, S. (2020). Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort. British Journal of Haematology, 191(5), 755-763. https://doi.org/10.1111/bjh.16720
Katagiri, S., Makishima, H., Azuma, K., Nannya, Y.,Saitoh, Y., Yoshizawa, S., Akahane, D., Fujimoto, H., Ito, Y., Velaga, R.,Umezu, T., Ohyashiki, J. H., Ogawa, S., & Ohyashiki, K. (2020). Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma. Haematologica, 105(7), E337-E339. https://doi.org/10.3324/haematol.2019.229856
Kimura, S., Seki, M., Kawai, T., Goto, H., Yoshida, K.,Isobe, T., Sekiguchi, M., Watanabe, K., Kubota, Y., Nannya, Y., Ueno, H.,Shiozawa, Y., Suzuki, H., Shiraishi, Y., Ohki, K., Kato, M., Koh, K.,Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N.,Manabe, A., Sanada, M., Mansour, M. R., Ohara, A., Horibe, K., Kobayashi, M.,Oka, A., Hayashi, Y., Miyano, S., Hata, K., Ogawa, S., & Takita, J.(2020). DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia, 34(4), 1163-1168. https://doi.org/10.1038/s41375-019-0626-2
Koyamaishi, S., Kamio, T., Kobayashi, A., Sato, T., Kudo,K., Sasaki, S., Kanezaki, R., Hasegawa, D., Muramatsu, H., Takahashi, Y.,Sasahara, Y., Hiramatsu, H., Kakuda, H., Tanaka, M., Ishimura, M., Nishi, M.,Ishiguro, A., Yabe, H., Sarashina, T., Yamamoto, M., Yuza, Y., Hyakuna, N.,Yoshida, K., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Miyano, S., Ogawa,S., Toki, T., Terui, K., & Ito, E. Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia. Bone Marrow Transplantation. https://doi.org/10.1038/s41409-020-01056-1
Kubota, Y., Seki, M., Kawai, T., Isobe, T., Yoshida, M.,Sekiguchi, M., Kimura, S., Watanabe, K., Sato-Otsubo, A., Yoshida, K., Suzuki,H., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Hiwatari, M.,Oka, A., Hayashi, Y., Miyano, S., Ogawa, S., Hata, K., Tanaka, Y., &Takita, J. (2020). Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets. Communications Biology, 3(1). https://doi.org/10.1038/s42003-020-01267-8
Li, X. Y., Turanli, B., Juszczak, K., Kim, W., Arif, M.,Sato, Y., Ogawa, S., Turkez, H., Nielsen, J., Boren, J., Uhlen, M.,Zhang, C., & Mardinoglu, A. (2020). Classification of clear cell renal cell carcinoma based on PKM alternative splicing. Heliyon, 6(2). https://doi.org/10.1016/j.heliyon.2020.e03440
Matsuo, H., Yoshida, K., Nakatani, K., Harata, Y.,Higashitani, M., Ito, Y., Kamikubo, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K.,Tanaka, H., Okada, A., Nannya, Y., Takeda, J., Ueno, H., Kiyokawa, N.,Tomizawa, D., Taga, T., Tawa, A., Miyano, S., Meggendorfer, M., Haferlach, C., Ogawa,S., & Adachi, S. (2020). Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML. Blood Advances, 4(19), 4623-4631. https://doi.org/10.1182/bloodadvances.2020002457
Mylonas, E., Yoshida, K., Frick, M., Hoyer, K., Christen,F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y.,Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C. C., Sawitzki, B., Schwarz, M.,Bullinger, L., le Coutre, P., Rose-Zerilli, M. J. J., Ogawa, S., & Damm, F. (2020). Single-cell analysis based dissection of clonality in myelofibrosis. Nature Communications, 11(1). https://doi.org/10.1038/s41467-019-13892-x
Ogura, H., Ohga, S., Aoki, T., Utsugisawa, T., Takahashi,H., Iwai, A., Watanabe, K., Okuno, Y., Yoshida, K., Ogawa, S., Miyano,S., Kojima, S., Yamamoto, T., Yamamoto-Shimojima, K., & Kanno, H. (2020). Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations. Human Genome Variation, 7(1). https://doi.org/10.1038/s41439-020-00130-w
Okano, T., Imai, K., Naruto, T., Okada, S., Yamashita, M.,Yeh, T. W., Ono, S., Tanaka, K., Okamoto, K., Tanita, K., Matsumoto, K.,Toyofuku, E., Kumaki-Matsumoto, E., Okamura, M., Ueno, H., Ogawa, S.,Ohara, O., Takagi, M., Kanegane, H., & Morio, T. (2020). Whole-Exome Sequencing-Based Approach for Germline Mutations in Patients with Inborn Errors of Immunity. Journal of Clinical Immunology, 40(5), 729-740. https://doi.org/10.1007/s10875-020-00798-3
Polprasert, C, Takeda, J, Niparuck, P, Rattanathammethee,T, Pirunsarn, A, Suksusut, A, Kobbuaklee, S, Wudhikarn, K, Lawasut, P,Kongkiatkamon, S, Chuncharunee, S, Songserm, K, Phowthongkum, P, Bunworasate,U, Nannya, Y, Yoshida, K, Makishima, H, Ogawa, S, & Rojnuckarin, P.(2020). Novel DDX41 variants in Thai patients with myeloid neoplasms. International Journal of Hematology, 111(2), 241-246. https://doi.org/10.1007/s12185-019-02770-3
Sekiguchi, M., Seki, M., Kawai, T., Yoshida, K., Yoshida,M., Isobe, T., Hoshino, N., Shirai, R., Tanaka, M., Souzaki, R., Watanabe, K.,Arakawa, Y., Nannya, Y., Suzuki, H., Fujii, Y., Kataoka, K., Shiraishi, Y.,Chiba, K., Tanaka, H., Shimamura, T., Sato, Y., Sato-Otsubo, A., Kimura, S.,Kubota, Y., Hiwatari, M., Koh, K., Hayashi, Y., Kanamori, Y., Kasahara, M.,Kohashi, K., Kato, M., Yoshioka, T., Matsumoto, K., Oka, A., Taguchi, T.,Sanada, M., Tanaka, Y., Miyano, S., Hata, K., Ogawa, S., & Takita,J. (2020). Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. Npj Precision Oncology,4(1). https://doi.org/10.1038/s41698-020-0125-y
Shrestha, R., Sakata-Yanagimoto, M., Maie, K., Oshima, M.,Ishihara, M., Suehara, Y., Fukumoto, K., Nakajima-Takagi, Y., Matsui, H., Kato,T., Muto, H., Sakamoto, T., Kusakabe, M., Nannya, Y., Makishima, H., Ueno, H.,Saiki, R., Ogawa, S., Chiba, K., Shiraishi, Y., Miyano, S., Mouly, E.,Bernard, O. A., Inaba, T., Koseki, H., Iwama, A., & Chiba, S. (2020). Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status. Blood Advances, 4(5), 845-854. https://doi.org/10.1182/bloodadvances.2019001324
Todisco, G., Creignou, M., Gall, A., Guglielmelli, P.,Rumi, E., Roncador, M., Rizzo, E., Nannya, Y., Pietra, D., Elena, C., Bono, E.,Molteni, E., Rosti, V., Catrical, S., Sarchi, M., Dimitriou, M., Ungerstedt,J., Vannucchi, A. M., Hellstrom-Lindberg, E., Ogawa, S., Cazzola, M.,& Malcovati, L. Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2(P95)-mutated neoplasms. Leukemia. https://doi.org/10.1038/s41375-020-01106-z
Ueno, H., Yoshida, K., Shiozawa, Y., Nannya, Y.,Iijima-Yamashita, Y., Kiyokawa, N., Shiraishi, Y., Chiba, K., Tanaka, H.,Isobe, T., Seki, M., Kimura, S., Makishima, H., Nakagawa, M. M., Kakiuchi, N.,Kataoka, K., Yoshizato, T., Nishijima, D., Deguchi, T., Ohki, K., Sato, A.,Takahashi, H., Hashii, Y., Tokimasa, S., Hara, J., Kosaka, Y., Kato, K.,Inukai, T., Takita, J., Imamura, T., Miyano, S., Manabe, A., Horibe, K., Ogawa,S., & Sanada, M. (2020). Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia. Blood Advances, 4(20), 5165-5173. https://doi.org/10.1182/bloodadvances.2019001307
Yasuda, T., Sanada, M., Nishijima, D., Kanamori, T.,Iijima, Y., Hattori, H., Saito, A., Miyoshi, H., Ishikawa, Y., Asou, N., Usuki,K., Hirabayashi, S., Kato, M., Ri, M., Handa, H., Ishida, T., Shibayama, H.,Abe, M., Iriyama, C., Karube, K., Nishikori, M., Ohshima, K., Kataoka, K.,Yoshida, K., Shiraishi, Y., Goto, H., Adachi, S., Kobayashi, R., Kiyoi, H.,Miyazaki, Y., Ogawa, S., Kurahashi, H., Yokoyama, H., Manabe, A., Iida,S., Tomita, A., & Horibe, K. (2020). Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study. Cancer Science, 111(9), 3367-3378. https://doi.org/10.1111/cas.14552
Bernard, E., Nannya, Y., Hasserjian, R. P., Devlin, S. M.,Tuechler, H., Medina-Martinez, J. S., Yoshizato, T., Shiozawa, Y., Saiki, R.,Malcovati, L., Levine, M. F., Arango, J. E., Zhou, Y. Y., Sole, F., Cargo, C.A., Haase, D., Creignou, M., Germing, U., Zhang, Y. M., Gundem, G., Sarian, A.,van de Loosdrecht, A. A., Jadersten, M., Tobiasson, M., Kosmider, O., Follo, M.Y., Thol, F., Pinheiro, R. F., Santini, V., Kotsianidis, I., Boultwood, J.,Santos, F. P. S., Schanz, J., Kasahara, S., Ishikawa, T., Tsurumi, H.,Takaori-Kondo, A., Kiguchi, T., Polprasert, C., Bennett, J. M., Klimek, V. M.,Savona, M. R., Belickova, M., Ganster, C., Palomo, L., Sanz, G., Ades, L.,Della Porta, M. G., Smith, A. G., Werner, Y., Patel, M., Viale, A., Vanness,K., Neuberg, D. S., Stevenson, K. E., Menghrajani, K., Bolton, K. L., Fenaux,P., Pellagatti, A., Platzbecker, U., Heuser, M., Valent, P., Chiba, S.,Miyazaki, Y., Finelli, C., Voso, M. T., Shih, L. Y., Fontenay, M., Jansen, J.H., Cervera, J., Atsuta, Y., Gattermann, N., Ebert, B. L., Bejar, R.,Greenberg, P. L., Cazzola, M., Hellstrom-Lindberg, E., Ogawa, S., & Papaemmanuil, E. (2020). Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature Medicine, 26(10), 1549-+. https://doi.org/10.1038/s41591-020-1008-z
Donovan, F. X., Solanki, A., Mori, M., Chavan, N., George,M., Kumar, C. S., Okuno, Y., Muramastsu, H., Yoshida, K., Shimamoto, A.,Takaori-Kondo, A., Yabe, H., Ogawa, S., Kojima, S., Yabe, M.,Ramanagoudr-Bhojappa, R., Smogorzewska, A., Mohan, S., Rajendran, A., Auerbach,A. D., Takata, M., Chandrasekharappa, S. C., & Vundinti, B. R. (2020). A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India. Human Mutation, 41(1), 122-128. https://doi.org/10.1002/humu.23914
Fujioka, M., Itonaga, H., Kato, T., Nannya, Y., Hashimoto,M., Kasai, S., Toriyama, E., Kamijo, R., Taguchi, M., Taniguchi, H., Sato, S.,Atogami, S., Imaizumi, Y., Hata, T., Moriuchi, Y., Ogawa, S., &Miyazaki, Y. (2020). Persistent clonal cytogenetic abnormality with del(20q)from an initial diagnosis of acute promyelocytic leukemia. International Journal of Hematology, 111(2), 311-316. https://doi.org/10.1007/s12185-019-02731-w
Gu, M. X., Zwiebel, M., Ong, S. H., Boughton, N.,Nomdedeu, J., Basheer, F., Nannya, Y., Quiros, P. M., Ogawa, S.,Cazzola, M., Rad, R., Butler, A. P., Vijayabaskar, M. S., & Vassiliou, G.S. (2020). RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing. Haematologica, 105(6), E290-E293. https://doi.org/10.3324/haematol.2019.230821
Hashimoto, M, Itonaga, H, Nannya, Y, Taniguchi, H, Fukuda,Y, Furumoto, T, Fujioka, M, Kasai, S, Taguchi, M, Sato, S, Sawayama, Y,Atogami, S, Iwasaki, K, Hata, T, Soda, H, Moriuchi, Y, Nakata, K, Ogawa, S,& Miyazaki, Y. (2020). Secondary Pulmonary Alveolar Proteinosis Following Treatment with Azacitidine for Myelodysplastic Syndrome. Internal Medicine,59(8), 1081-1086. https://doi.org/10.2169/internalmedicine.3770-19
Imataki, O., Ishida, T., Kubo, H., Uemura, M., Nanya, Y.,Kawakami, K., Ogawa, S., & Kadowaki, N. (2020). A Case of TyrosineKinase Inhibitor-Resistant Chronic Myeloid Leukemia, Chronic Phase with ASXL1 Mutation. Case Reports in Oncology, 13(1), 449-455. https://doi.org/10.1159/000506452
Jo, T., Nishikori, M., Kogure, Y., Arima, H., Sasaki, K.,Sasaki, Y., Nakagawa, T., Iwai, F., Momose, S., Shiraishi, A., Kiyonari, H.,Kagaya, N., Onuki, T., Shin-ya, K., Yoshida, M., Kataoka, K., Ogawa, S.,Iwai, K., & Takaori-Kondo, A. (2020). LUBAC accelerates B-celllymphomagenesis by conferring resistance to genotoxic stress on B cells. Blood,136(6), 684-697. https://doi.org/10.1182/blood.2019002654
Madan, V, Li, J, Zhou, SQ, Teoh, WW, Han, L, Meggendorfer,M, Malcovati, L, Cazzola, M, Ogawa, S, Haferlach, T, Yang, H, & Koeffler, HP. (2020). Distinct and convergent consequences of splice factormutations in myelodysplastic syndromes. American Journal of Hematology, 95(2),133-143. https://doi.org/10.1002/ajh.25673
Mori, M, Hira, A, Yoshida, K, Muramatsu, H, Okuno, Y,Shiraishi, Y, Anmae, M, Yasuda, J, Tadaka, S, Kinoshita, K, Osumi, T, Noguchi,Y, Adachi, S, Kobayashi, R, Kawabata, H, Imai, K, Morio, T, Tamura, K,Takaori-Kondo, A, Yamamoto, M, Miyano, S, Kojima, S, Ito, E, Ogawa, S,Matsuo, K, Yabe, H, Yabe, M, & Takata, M. (2020). Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients (vol ,104pg 1962, 2019). Haematologica, 105(4), 1166-1167. https://doi.org/10.3324/haematol.2019.245720
Nakagama, Y, Takeda, N, Ogawa, S, Takeda, H,Furutani, Y, Nakanishi, T, Sato, T, Hirata, Y, Oka, A, & Inuzuka, R.(2020). Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish. Molecular Genetics & Genomic Medicine, 8(3). https://doi.org/10.1002/mgg3.1107
Nguyen, M. A. T., Hosokawa, K., Yoroidaka, T., Maruyama,H., Espinoza, J. L., Elbadry, M. I., Mohiuddin, M., Tanabe, M., Katagiri, T.,Nakagawa, N., Chonabayashi, K., Yoshida, Y., Arima, N., Kashiwase, K., Saji,H., Ogawa, S., & Nakao, S. (2020). Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia. Immunohorizons,4(7), 430-441. https://doi.org/10.4049/immunohorizons.2000046
Nguyen, T. B., Sakata-Yanagimoto, M., Fujisawa, M., Nuhat,S. T., Miyoshi, H., Nannya, Y., Hashimoto, K., Fukumoto, K., Bernard, O. A.,Kiyoki, Y., Ishitsuka, K., Momose, H., Sukegawa, S., Shinagawa, A., Suyama, T.,Sato, Y., Nishikii, H., Obara, N., Kusakabe, M., Yanagimoto, S., Ogawa, S.,Ohshima, K., & Chiba, S. (2020). Dasatinib Is an Effective Treatment forAngioimmunoblastic T-cell Lymphoma. Cancer Research, 80(9), 1875-1884. https://doi.org/10.1158/0008-5472.can-19-2787
Secardin, L., Limia, C. E. G., di Stefano, A., Bonamino,M. H., Saliba, J., Kataoka, K., Rehen, S. K., Raslova, H., Marty, C., Ogawa,S., Vainchenker, W., Monte-Mor, B. D. R., & Ploa, I. (2020). TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells. Stem Cell Research, 44. https://doi.org/10.1016/j.scr.2020.101755
Shirai, R., Osumi, T., Terashima, K., Kiyotani, C.,Uchiyama, M., Tsujimoto, S., Yoshida, M., Yoshida, K., Uchiyama, T., Tomizawa,D., Shioda, Y., Sekiguchi, M., Watanabe, K., Keino, D., Ueno-Yokohata, H.,Ohki, K., Takita, J., Ito, S., Deguchi, T., Kiyokawa, N., Ogiwara, H., Hishiki,T., Ogawa, S., Okita, H., Matsumoto, K., Yoshioka, T., & Kato, M.(2020). High prevalence of SMARCB1 constitutional abnormalities including mosaicism in malignant rhabdoid tumors. European Journal of Human Genetics,28(8), 1124-1128. https://doi.org/10.1038/s41431-020-0614-z
Taguchi, M., Mishima, H., Shiozawa, Y., Hayashida, C.,Kinoshita, A., Nannya, Y., Makishima, H., Horai, M., Matsuo, M., Sato, S.,Itonaga, H., Kato, T., Taniguchi, H., Imanishi, D., Imaizumi, Y., Hata, T.,Takenaka, M., Moriuchi, Y., Shiraishi, Y., Miyano, S., Ogawa, S.,Yoshiura, K. I., & Miyazaki, Y. (2020). Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki. Haematologica, 105(2),358-365. https://doi.org/10.3324/haematol.2019.219386
Review Articles
Ogawa, S. (2020). Genetic basis of myelodysplastic syndromes. Proceedings of the Japan Academy Series B – Physical and Biological Sciences, 96(3), 107-121. https://doi.org/10.2183/pjab.96.009
Malcovati, L., Stevenson, K., Papaemmanuil, E., Neuberg,D., Bejar, R., Boultwood, J., Bowen, D. T., Campbell, P. J., Ebert, B. L.,Fenaux, P., Haferlach, T., Heuser, M., Jansen, J. H., Komrokji, R. S., Maciejewski,J. P., Walter, M. J., Fontenay, M., Garcia-Manero, G., Graubert, T. A., Karsan,A., Meggendorfer, M., Pellagatti, A., Sallman, D. A., Savona, M. R., Sekeres,M. A., Steensma, D. P., Tauro, S., Thol, F., Vyas, P., Van de Loosdrecht, A.A., Haase, D., Tuchler, H., Greenberg, P. L., Ogawa, S.,Hellstrom-Lindberg, E., & Cazzola, M. (2020). SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS. Blood, 136(2), 157-170. https://doi.org/10.1182/blood.2020004850
2019
Original Papers
Berger, G., Gerritsen, M., Yi, G. Q., Koorenhof-Scheele, T. N., Kroeze, L. I., Stevens-Kroef, M., Yoshida, K., Shiraishi, Y., van den Berg, E., Schepers, H., Huls, G., Mulder, A. B., Ogawa, S., Martens, J. H. A., Jansen, J. H., &Vellenga, E. (2019). Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern. Blood Advances, 3(20), 3111-3122. https://doi.org/10.1182/bloodadvances.2019000518
Shiba, N., Yoshida, K., Hara, Y., Yamato, G., Shiraishi, Y., Matsuo, H., Okuno, Y., Chiba, K., Tanaka, H., Kaburagi, T., Takeuchi, M., Ohki, K., Sanada, M., Okubo, J., Tomizawa, D., Taki, T., Shimada, A., Sotomatsu, M., Horibe, K., Taga, T., Adachi, S., Tawa, A., Miyano, S., Ogawa, S., & Hayashi, Y. (2019). Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia. Blood Advances, 3(20), 3157-3169. https://doi.org/10.1182/bloodadvances.2019000404
Adachi, M, Yoshida, K, Shiraishi, Y, Chiba, K, Miyano, S, & Ogawa, S. (2019). Successful treatment of pure red cell aplasia with cyclosporin in a patientwith T-cell large granular lymphocytic leukemia harboring the STAT3 D661Vmutation. [Rinsho ketsueki] The Japanese journal of clinical hematology, 60(1), 39-45. https://doi.org/10.11406/rinketsu.60.39
Ahn, J.S., Kim, T., Kim, Y. K., Cho, Y. C., Cho, S., Jung, S. N., Ahn, S. Y., Jung, S.Y., Yang, D. H., Lee, J. J., Choi, S., Lee, J. Y., Shin, M. G., Yoshida, K., Ogawa, S., Kim, I. C., Zhang, Z. L., Kim, H. J., & Kim, D. D. H. (2019). Remission clone in acute myeloid leukemia shows growth advantage after chemotherapy butis distinct from leukemic clone. Experimental Hematology, 75, 26-30. https://doi.org/10.1016/j.exphem.2019.06.001
Becker, H., Greve, G., Kataoka, K., Mallm, J. P., Duque-Afonso, J., Ma, T., Niemoller, C., Pantic, M., Duyster, J., Cleary, M. L., Schuler, J., Rippe, K., Ogawa, S., & Lubbert, M. (2019). Identification of enhancer of mRNA decapping 4 as anovel fusion partner of MLL in acute myeloid leukemia. Blood Advances, 3(5), 761-765. https://doi.org/10.1182/bloodadvances.2018023879
Cao-Sy, L., Obara, N., Sakamoto, T., Kato, T., Hattori, K., Sakashita, S., Nannya, Y., Ogawa, S., Harada, H., Sakata-Yanagimoto, M., Nishikii, H., & Chiba, S. (2019). Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis. International Journal ofHematology, 109(3), 309-318. https://doi.org/10.1007/s12185-018-02576-9
Chonabayashi, K., Yoshida, Y., Kitawaki, T., Nannya, Y., Nakamura, M., Oshima, S., Hishizawa, M., Yamashita, K., Ogawa, S., & Takaori-Kondo, A. (2019). Acute myeloidleukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dosemethotrexate therapy for rheumatoid arthritis. Annals of Hematology, 98(12), 2841-2843. https://doi.org/10.1007/s00277-019-03838-0
Christen, F., Hoyer, K., Yoshida, K., Hou, H. A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W. C., Blau, I. W., Tang, J. L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Lowenberg, B., Linch, D. C., Bullinger, L., Valk, P. J. M., Tien, H. F., Gale, R. E., Ogawa, S., & Damm, F. (2019). Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international studyon 331 patients. Blood, 133(10), 1140-1151. https://doi.org/10.1182/blood-2018-05-852822
Chung, E. Y., Mai, Y., Shah, U. A., Wei, Y. Q., Ishida, E., Kataoka, K., Ren, X. X., Pradhan, K., Bartholdy, B., Wei, X. L., Zou, Y. Y., Zhang, J. H., Ogawa, S., Steidl, U., Zang, X. X., Verma, A., Janakiram, M., & Ye, B. H. (2019). PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of AdultT-Cell Leukemia/Lymphoma. Clinical Cancer Research, 25(12), 3589-3601. https://doi.org/10.1158/1078-0432.ccr-18-3033
Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Chonabayashi, K., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M.A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K., & Nakao, S. (2019). Escape hematopoiesis by HLA-B5401-lacking hematopoietic stemprogenitor cells in men with acquired aplastic anemia. Haematologica, 104(10), E447-E450. https://doi.org/10.3324/haematol.2018.210856
Frick, M., Chan, W., Arends, C. M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhauser, M., Blau, I. W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E. M., Spriewald, B. M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socie, G., Kroeger, N., Bullinger, L., Thiede, C., & Damm, F. (2019). Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation. Journalof Clinical Oncology, 37(5), 375-+. https://doi.org/10.1200/jco.2018.79.2184
Funakoshi, T., Miyamoto, S., Kakiuchi, N., Nikaido, M., Setoyama, T., Yokoyama, A., Horimatsu, T., Yamada, A., Torishima, M., Kosugi, S., Yamada, H., Sugimura, H., Haga, H., Sakai, Y., Ogawa, S., Seno, H., Muto, M., & Chiba, T. (2019). Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer. GastricCancer, 22(4), 892-898. https://doi.org/10.1007/s10120-018-00912-w
Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M.A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida, K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E., Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Ades, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellstrom-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tuchler, H., Greenberg, P. L., Bejar, R., & IntWorking Grp, M. D. S. Mol Progno. (2019). TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia, 33(7), 1747-1758. https://doi.org/10.1038/s41375-018-0351-2
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Review Article
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