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小川グループ

2022

原著論文

Mori, T., Okamoto, Y., Mu, A. F., Ide, Y., Yoshimura, A., Senda, N., Inagaki-Kawata, Y., Kawashima, M., Kitao, H., Tokunaga, E., Miyoshi, Y., Ohsumi, S., Tsugawa, K., Ohta, T., Katagiri, T., Ohtsuru, S., Koike, K., Ogawa, S., Toi, M., Iwata, H., Nakamura, S., Matsuo, K., & Takata, M. (2023). Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2-mutation carriers. Cancer Medicine, 12(6), 6594-6602. doi:10.1002/cam4.5430

Watase, M., Masaki, K., Chubachi, S., Namkoong, H., Tanaka, H., Lee, H., Fukushima, T., Otake, S., Nakagawara, K., Kusumoto, T., Asakura, T., Kamata, H., I, Mutoh, Y., Suzuki, Y., Edahiro, R., Sano, H., Sato, Y., Okada, Y., Koike, R., Kitagawa, Y., Tokunaga, K., Kimura, A., Imoto, S., Miyano, S., Ogawa, S.,shii, M., Hasegawa, N., Oyamada, Y., Harada, N., Ueda, T., Ueda, S., Ishiguro, T., Arimura, K., Saito, F., Yoshiyama, T., Nakano, Y. Kanai, T., Fukunaga, K., & Japan, C.-T. F. (2023). Impact of accumulative smoking exposure and chronic obstructive pulmonary disease on COVID-19 outcomes: report based on findings from the Japan COVID-19 task force. International Journal of Infectious Diseases, 128, 121-127. doi:10.1016/j.ijid.2022.12.019

Butler-Laporte, G., Povysil, G., Kosmicki, J. A., Cirulli, E. T., Drivas, T., Furini, S., Saad, C., Schmidt, A., Olszewski, P., Korotko, U., Quinodoz, M., Celik, E., Kundu, K., Walter, K., Jung, J., Stockwell, A. D., Sloofman, L. G., Jordan, D. M., Thompson, R. C., Del Valle, D., Simons, N., Cheng, E., Sebra, R., Schadt, E. E., Kim-Schulze, S., Gnjatic, S., Merad, M., Buxbaum, J. D., Beckmann, N. D., Charney, A. W., Przychodzen, B., Chang, T., Pottinger, T. D., Shang, N., Brand, F., Fava, F., Mari, F., Chwialkowska, K., Niemira, M., Pula, S., Baillie, J. K., Stuckey, A., Salas, A., Bello, X., Pardo-Seco, J., Gomez-Carballa, A., Rivero-Calle, I., Martinon-Torres, F., Ganna, A., Karczewski, K. J., Veerapen, K., Bourgey, M., Bourque, G., Eveleigh, R. J., Forgetta, V., Morrison, D., Langlais, D., Lathrop, M., Mooser, V., Nakanishi, T., Frithiof, R., Hultstrom, M., Lipcsey, M., Marincevic-Zuniga, Y., Nordlund, J., Barrett, K. M. S., Lee, W., Bolze, A., White, S., Riffle, S., Tanudjaja, F., Sandoval, E., Neveux, I., Dabe, S., Casadei, N., Motameny, S., Alaamery, M., Massadeh, S., Aljawini, N., Almutairi, M. S., Arabi, Y. M., Alqahtani, S. A., Al Harthi, F. S., Almutairi, A., Alqubaishi, F., Alotaibi, S., Binowayn, A., Alsolm, E. A., El Bardisy, H., Fawzy, M., Cai, F., Soranzo, N., Butterworth, A., Geschwind, D. H., Arteaga, S., Stephens, A., Butte, M. J., Boutros, P. C., Yamaguchi, T. N., Tao, S., Eng, S., Sanders, T., Tung, P. J., Broudy, M. E., Pan, Y., Gonzalez, A., Chavan, N., Johnson, R., Pasaniuc, B., Yaspan, B., Smieszek, S., Rivolta, C., Bibert, S., Bochud, P. Y., Dabrowski, M., Zawadzki, P., Sypniewski, M., Kaja, E., Chariyavilaskul, P., Nilaratanakul, V., Hirankarn, N., Shotelersuk, V., Pongpanich, M., Phokaew, C., Chetruengchai, W., Tokunaga, K., Sugiyama, M., Kawai, Y., Hasegawa, T., Naito, T., Namkoong, H., Edahiro, R., Kimura, A., Ogawa, S., Kanai, T., Fukunaga, K., Okada, Y., Imoto, S., Miyano, S., Mangul, S., Abedalthagafi, M. S., Zeberg, H., Grzymski, J. J., Washington, N. L., Ossowski, S., Ludwig, K. U., Schulte, E. C., Riess, O., Moniuszko, M., Kwasniewski, M., Mbarek, H., Ismail, S. I., Verma, A., Goldstein, D. B., Kiryluk, K., Renieri, A., Ferreira, M. A. R., Richards, J. B., Initiative, C.-H. G., De, C. O. I. H. G. G., Study, G.-C. M., Mt Sinai Clinical Intelligence, C., Consortium, G.-C., Gen, O. C., Japan, C.-T. F., & Regeneron Genetics, C. (2022). Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. Plos Genetics, 18(11). doi:10.1371/journal.pgen.1010367

Guzzi, N., Muthukumar, S., Ciesla, M., Todisco, G., Ngoc, P. C. T., Madej, M., Munita, R., Fazio, S., Ekstrom, S., Mortera-Blanco, T., Jansson, M., Nannya, Y., Cazzola, M., Ogawa, S., Malcovati, L., Hellstrom-Lindberg, E., Dimitriou, M., & Bellodi, C. (2022). Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome. Nature Cell Biology, 24(3), 299-+. doi:10.1038/s41556-022-00852-9

Kato, H., Maezawa, Y., Nishijima, D., Iwamoto, E., Takeda, J., Kanamori, T., Yamaga, M., Mishina, T., Takeda, Y., Izumi, S., Hino, Y., Nishi, H., Ishiko, J., Takeuchi, M., Kaneko, H., Koshizaka, M., Mimura, N., Kuzuya, M., Sakaida, E., Takemoto, M., Shiraishi, Y., Miyano, S., Ogawa, S., Iwama, A., Sanada, M., & Yokote, K. (2022). A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency. Experimental Hematology, 109, 11-17. doi:10.1016/j.exphem.2022.02.005

Li, X. Y., Shong, K., Kim, W., Yuan, M., Yang, H., Sato, Y., Kume, H., Ogawa, S., Turkez, H., Shoaie, S., Boren, J., Nielsen, J., Uhlen, M., Zhang, C., & Mardinoglu, A. (2022). Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach. Ebiomedicine, 78. doi:10.1016/j.ebiom.2022.103963

Mikami, T., Kato, I., Wing, J. B., Ueno, H., Tasaka, K., Tanaka, K., Kubota, H., Saida, S., Umeda, K., Hiramatsu, H., Isobe, T., Hiwatari, M., Okada, A., Chiba, K., Shiraishi, Y., Tanaka, H., Miyano, S., Arakawa, Y., Oshima, K., Koh, K., Adachi, S., Iwaisako, K., Ogawa, S., Sakaguchi, S., & Takita, J. (2022). Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia. Cancer Sci, 113(1), 41-52. doi:10.1111/cas.15186

Morita, Y., Nannya, Y., Ichikawa, M., Hanamoto, H., Shibayama, H., Maeda, Y., Hata, T., Miyamoto, T., Kawabata, H., Takeuchi, K., Tanaka, H., Kishimoto, J., Miyano, S., Matsumura, I., Ogawa, S., Akashi, K., Kanakura, Y., & Mitani, K. (2022). ASXL1 mutations with serum EPO levels predict poor response to darbepoetin alfa in lower-risk MDS: W-JHS MDS01 trial. International Journal of Hematology, 116(5), 659-668. doi:10.1007/s12185-022-03414-9

Nakagawara, K., Chubachi, S., Namkoong, H., Tanaka, H., Lee, H., Azekawa, S., Otake, S., Fukushima, T., Morita, A., Watase, M., Sakurai, K., Kusumoto, T., Asakura, T., Masaki, K., Kamata, H., Ishii, M., Hasegawa, N., Harada, N., Ueda, T., Ueda, S., Ishiguro, T., Arimura, K., Saito, F., Yoshiyama, T., Nakano, Y., Mutoh, Y., Suzuki, Y., Edahiro, R., Murakami, K., Sato, Y., Okada, Y., Koike, R., Kitagawa, Y., Tokunaga, K., Kimura, A., Imoto, S., Miyano, S., Ogawa, S., Kanai, T., & Fukunaga, K. (2022). Impact of upper and lower respiratory symptoms on COVID-19 outcomes: a multicenter retrospective cohort study. Respiratory Research, 23(1). doi:10.1186/s12931-022-02222-3

Namkoong, H., Edahiro, R., Takano, T., Nishihara, H., Shirai, Y., Sonehara, K., Tanaka, H., Azekawa, S., Mikami, Y., Lee, H., Hasegawa, T., Okudela, K., Okuzaki, D., Motooka, D., Kanai, M., Naito, T., Yamamoto, K., Wang, Q. B. S., Saiki, R., Ishihara, R., Matsubara, Y., Hamamoto, J., Hayashi, H., Yoshimura, Y., Tachikawa, N., Yanagita, E., Hyugaji, T., Shimizu, E., Katayama, K., Kato, Y., Morita, T., Takahashi, K., Harada, N., Hiki, M., Matsushita, Y., Takagi, H., Aoki, R., Nakamura, A., Harada, S., Sasano, H., Kabata, H., Masaki, K., Kamata, H., Ikemura, S., Chubachi, S., Okamori, S., Terai, H., Morita, A., Asakura, T., Sasaki, J., Morisaki, H., Uwamino, Y., Nanki, K., Uchida, S., Uno, S., Nishimura, T., Ishiguro, T., Isono, T., Shibata, S., Matsui, Y., Hosoda, C., Takano, K., Nishida, T., Kobayashi, Y., Takaku, Y., Takayanagi, N., Ueda, S., Tada, A., Miyawaki, M., Yamamoto, M., Yoshida, E., Hayashi, R., Nagasaka, T., Arai, S., Kaneko, Y., Sasaki, K., Tagaya, E., Kawana, M., Arimura, K., Anzai, T., Ito, S., Endo, A., Uchimura, Y., Miyazaki, Y., Honda, T., Tateishi, T., Tohda, S., Ichimura, N., Sonobe, K., Sassa, C. T., Nakajima, J., Nakano, Y., Nakajima, Y., Anan, R., Arai, R., Kurihara, Y., Harada, Y., Nishio, K., Ueda, T., Azuma, M., Saito, R., Sado, T., Sato, R., Haruta, Y., Nagasaki, T., Yasui, Y., Hasegawa, Y., Mutoh, Y., Kimura, T., Sato, T., Takei, R., Hagimoto, S., Noguchi, Y., Yamano, Y., Ota, S., Nakamori, Y., Yoshiya, K., Saito, F., Yoshihara, T., Wada, D., Iwamura, H., Kanayama, S., Maruyama, S., Yoshiyama, T., Ohta, K., Kokuto, H., Ogata, H., Tanaka, Y., Arakawa, K., Shimoda, M., Osawa, T., Tateno, H., Hase, I., Yoshida, S., Suzuki, S., Kawada, M., Horinouchi, H., Mitamura, K., Hagihara, M., Ochi, J., Uchida, T., Baba, R., Arai, D., Ogura, T., Takahashi, H., Hagiwara, S., Nagao, G., Konishi, S., Nakachi, I., Murakami, K., Yamada, M., Sugiura, H., Sano, H., Matsumoto, S., Kimura, N., Ono, Y., Baba, H., Suzuki, Y., Nakayama, S., Masuzawa, K., Namba, S., Suzuki, K., Naito, Y., Liu, Y. C., Takuwa, A., Sugihara, F., Wing, J. B., Sakakibara, S., Hizawa, N., Shiroyama, T., Miyawaki, S., Kawamura, Y., Nakayama, A., Matsuo, H., Maeda, Y., Nii, T., Noda, Y., Niitsu, T., Adachi, Y., Enomoto, T., Amiya, S., Hara, R., Yamaguchi, Y., Murakami, T., Kuge, T., Matsumoto, K., Yamamoto, Y., Yoneda, M., Kishikawa, T., Yamada, S., Kawabata, S., Kijima, N., Takagaki, M., Sasa, N., Ueno, Y., Suzuki, M., Takemoto, N., Eguchi, H., Fukusumi, T., Imai, T., Fukushima, M., Kishima, H., Inohara, H., Tomono, K., Kato, K., Takahashi, M., Matsuda, F., Hirata, H., Takeda, Y., Koh, H., Manabe, T., Funatsu, Y., Ito, F., Fukui, T., Shinozuka, K., Kohashi, S., Miyazaki, M., Shoko, T., Kojima, M., Adachi, T., Ishikawa, M., Inoue, T., Hirano, T., Kobayashi, K., Takaoka, H., Watanabe, K., Miyazawa, N., Kimura, Y., Sado, R., Sugimoto, H., Kamiya, A., Kuwahara, N., Fujiwara, A., Matsunaga, T., Sato, Y., Okada, T., Hirai, Y., Kawashima, H., Narita, A., Niwa, K., Sekikawa, Y., Nishi, K., Nishitsuji, M., Tani, M., Suzuki, J., Nakatsumi, H., Kitamura, H., Hagiwara, E., Murohashi, K., Okabayashi, H., Mochimaru, T., Nukaga, S., Satomi, R., Oyamada, Y., Mori, N., Baba, T., Fukui, Y., Odate, M., Mashimo, S., Makino, Y., Yagi, K., Hashiguchi, M., Kagyo, J., Shiomi, T., Fuke, S., Saito, H., Tsuchida, T., Fujitani, S., Takita, M., Morikawa, D., Yoshida, T., Izumo, T., Inomata, M., Kuse, N., Awano, N., Tone, M., Ito, A., Nakamura, Y., Hoshino, K., Maruyama, J., Ishikura, H., Takata, T., Odani, T., Amishima, M., Hattori, T., Shichinohe, Y., Kagaya, T., Kita, T., Sakagami, S., Koshida, K., Hayashi, K., Shimizu, T., Kozu, Y., Hiranuma, H., Gon, Y., Izumi, N., Nagata, K., Ueda, K., Taki, R., Hanada, S., Kawamura, K., Ichikado, K., Nishiyama, K., Muranaka, H., Nakamura, K., Hashimoto, N., Wakahara, K., Sakamoto, K., Omote, N., Ando, A., Kodama, N., Kaneyama, Y., Maeda, S., Kuraki, T., Matsumoto, T., Yokote, K., Nakada, T. A., Abe, R., Oshima, T., Shimada, T., Harada, M., Takahashi, T., Ono, H., Sakurai, T., Shibusawa, T., Kimizuka, Y., Kawana, A., Sano, T., Watanabe, C., Suematsu, R., Sageshima, H., Yoshifuji, A., Ito, K., Takahashi, S., Ishioka, K., Nakamura, M., Masuda, M., Wakabayashi, A., Watanabe, H., Nishikawa, M., Chihara, Y., Takeuchi, M., Onoi, K., Shinozuka, J., Sueyoshi, A., Nagasaki, Y., Okamoto, M., Ishihara, S., Shimo, M., Tokunaga, Y., Kusaka, Y., Ohba, T., Isogai, S., Ogawa, A., Fukuyama, S., Eriguchi, Y., Yonekawa, A., Kan-o, K., Kanaoka, K., Ihara, S., Komuta, K., Inoue, Y., Chiba, S., Yamagata, K., Hiramatsu, Y., Kai, H., Asano, K., Oguma, T., Ito, Y., Hashimoto, S., Yamasaki, M., Kasamatsu, Y., Komase, Y., Hida, N., Tsuburai, T., Oyama, B., Takada, M., Kanda, H., Kitagawa, Y., Fukuta, T., Miyake, T., Ogura, S., Abe, S., Kono, Y., Togashi, Y., Takoi, H., Kikuchi, R., Ogawa, S., Ogata, T., Kanehiro, A., Ozaki, S., Fuchimoto, Y., Wada, S., Fujimoto, N., Terashima, M., Beppu, S., Yoshida, K., Narumoto, O., Nagai, H., Ooshima, N., Motegi, M., Umeda, A., Miyagawa, K., Shimada, H., Endo, M., Ohira, Y., Watanabe, M., Inoue, S., Igarashi, A., Sato, M., Sagara, H., Tanaka, A., Ohta, S., Shibata, Y., Tanino, Y., Nikaido, T., Minemura, H., Yamada, Y., Hashino, T., Shinoki, M., Iwagoe, H., Fujii, K., Kishi, H., Imamura, T., Yamashita, T., Yatomi, M., Maeno, T., Hayashi, S., Kuramochi, M., Kamimaki, I., Tominaga, Y., Ishii, T., Utsugi, M., Ono, A., Tanaka, T., Kashiwada, T., Fujita, K., Saito, Y., Seike, M., Matsuse, H., Kodaka, N., Nakano, C., Oshio, T., Hirouchi, T., Makino, S., Egi, M., Omae, Y., Nannya, Y., Ueno, T., Ai, M., Kumanogoh, A., Hasegawa, N., Tokunaga, K., Ishii, M., Koike, R., Kimura, A., Imoto, S., Miyano, S., Kanai, T., Fukunaga, K., & Okada, Y. (2022). DOCK2 is involved in the host genetics and biology of severe COVID-19. Nature, 609(7928), 754-+. doi:10.1038/s41586-022-05163-5

Ogasawara, T., Fujii, Y., Kakiuchi, N., Shiozawa, Y., Sakamoto, R., Ogawa, Y., Ootani, K., Ito, E., Tanaka, T., Watanabe, K., Yoshida, Y., Kimura, N., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., & Ogawa, S. (2022). Genetic Analysis of Pheochromocytoma and Paraganglioma Complicating Cyanotic Congenital Heart Disease. Journal of Clinical Endocrinology & Metabolism, 107(9), 2545-2555. doi:10.1210/clinem/dgac362

Ogawa, S. (2022). Targeting lineage plasticity overcomes chemoresistance. Cancer Cell, 40(9), 905-907. doi:10.1016/j.ccell.2022.08.020

Sagawa, R., Sakata, S., Gong, B., Seto, Y., Takemoto, A., Takagi, S., Ninomiya, H., Yanagitani, N., Nakao, M., Mun, M., Uchibori, K., Nishio, M., Miyazaki, Y., Shiraishi, Y., Ogawa, S., Kataoka, K., Fujita, N., Takeuchi, K., & Katayama, R. (2022). Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation. Jci Insight, 7(1). doi:10.1172/jci.insight.153323

Sato-Otsubo, A., Osumi, T., Yoshida, M., Iguchi, A., Fukushima, T., Nakabayashi, K., Ogawa, S., Hata, K., & Kato, M. (2022). Genomic analysis of two rare cases of pediatric Ph-positive T-ALL. Pediatr Blood Cancer, 69(3), e29427. doi:10.1002/pbc.29427

Shingaki, S., Koya, J., Yuasa, M., Saito, Y., Tabata, M., McClure, M. B., Ogawa, S., Katayama, K., Togashi, Y., Imoto, S., Kogure, Y., & Kataoka, K. Tumor-promoting function and regulatory landscape of PD-L2 in B-cell lymphoma. Leukemia. doi:10.1038/s41375-022-01772-1

Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B. M., Bullinger, L., Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S., & Damm, F. (2022). The landscape of genetic aberrations in myxofibrosarcoma. International Journal of Cancer, 151(4), 565-577. doi:10.1002/ijc.34051

Tasaka, K., Ueno, H., Yamasaki, K., Okuno, T., Isobe, T., Kimura, S., Umeda, K., Hara, J., Ogawa, S., & Takita, J. (2022). Oncogenic FGFR1 mutation and amplification in common cellular origin in a composite tumor with neuroblastoma and pheochromocytoma. Cancer Science, 113(4), 1535-1541. doi:10.1111/cas.15260

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総説論文

Ogawa, S. (2020). Genetic basis of myelodysplastic syndromes. Proceedings of the Japan Academy Series B – Physical and Biological Sciences, 96(3), 107-121. https://doi.org/10.2183/pjab.96.009

Malcovati, L., Stevenson, K., Papaemmanuil, E., Neuberg,D., Bejar, R., Boultwood, J., Bowen, D. T., Campbell, P. J., Ebert, B. L.,Fenaux, P., Haferlach, T., Heuser, M., Jansen, J. H., Komrokji, R. S., Maciejewski,J. P., Walter, M. J., Fontenay, M., Garcia-Manero, G., Graubert, T. A., Karsan,A., Meggendorfer, M., Pellagatti, A., Sallman, D. A., Savona, M. R., Sekeres,M. A., Steensma, D. P., Tauro, S., Thol, F., Vyas, P., Van de Loosdrecht, A.A., Haase, D., Tuchler, H., Greenberg, P. L., Ogawa, S.,Hellstrom-Lindberg, E., & Cazzola, M. (2020). SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS. Blood, 136(2), 157-170. https://doi.org/10.1182/blood.2020004850

2019

原著論文

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総説論文

Ogawa, S. (2019). Genetics of MDS. Blood, 133(10), 1049-1059. https://doi.org/10.1182/blood-2018-10-844621