Single-cell Genome Information Analysis Core (SignAC), the core facility of ASHBi at Kyoto University, maintains and manages state-of-the-art shared equipment. Through its unique research and development activities, it is also dedicated to building a system for the comprehensive analysis of individual cell characteristics, including epigenomic states. Thus, SignAC aims to become a central hub, supporting cross-disciplinary research within ASHBi and various fields at Kyoto University and beyond.