Publications supported by SignAC

2022

・Imoto Y, Nakamura T, Escolar EG, Yoshiwaki M, Kojima Y, Yabuta Y, Katou Y, Yamamoto T, Hiraoka Y, Saitou M.
Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis.
Life Sci Alliance. 2022 Aug 9;5(12):e202201591. doi: 10.26508/lsa.202201591. PMID: 35944930; PMCID: PMC9363502.

・Mizuta K, Katou Y, Nakakita B, Kishine A, Nosaka Y, Saito S, Iwatani C, Tsuchiya H, Kawamoto I, Nakaya M, Tsukiyama T, Nagano M, Kojima Y,
Nakamura T, Yabuta Y, Horie A, Mandai M, Ohta H, Saitou M.
Ex vivo reconstitution of fetal oocyte development in humans and cynomolgus monkeys.
EMBO J. 2022 Aug 1:e110815. doi: 10.15252/embj.2022110815. Epub ahead of print. PMID: 35912849.

・Ichijo R, Maki K, Kabata M, Murata T, Nagasaka A, Ishihara S, Haga H, Honda T, Adachi T, Yamamoto T, Toyoshima F.
Vasculature atrophy causes a stiffened microenvironment that augments epidermal stem cell differentiation in aged skin.
Nat Aging. 2022 July 11; 2(7):592–600. doi: 10.1038/s43587-022-00244-6.

・Ohgushi M, Taniyama N, Vandenbon A, Eiraku M.
Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model.
Cell Rep. 2022 Jun 21;39(12):110973. doi: 10.1016/j.celrep.2022.110973. PMID: 35732132.

・Nagano M, Hu B, Yokobayashi S, Yamamura A, Umemura F, Coradin M, Ohta H, Yabuta Y, Ishikura Y, Okamoto I, Ikeda H, Kawahira N,
Nosaka Y, Shimizu S, Kojima Y, Mizuta K, Kasahara T, Imoto Y, Meehan K, Stocsits R, Wutz G, Hiraoka Y, Murakawa Y, Yamamoto T,
Tachibana K, Peters JM, Mirny LA, Garcia BA, Majewski J, Saitou M.
Nucleome programming is required for the foundation of totipotency in mammalian germline development.
EMBO J. 2022 Jul 4;41(13):e110600. doi: 10.15252/embj.2022110600. Epub 2022 Jun 15. PMID: 35703121; PMCID: PMC9251848.

・Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O.
Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases.
Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11. PMID: 35544597.

・Ito K, Nagata K, Ohta S, Matsuda Y, Ukai T, Yasuda I, Ota A, Kobayashi R, Kabata M, Sankoda N, Maeda T, Woltjen K, Yang L, Maruyama R,
Katayama R, Yamamoto T, Yamada Y.
The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Cell Rep. 2022 Apr 26;39(4):110721. doi: 10.1016/j.celrep.2022.110721. PMID: 35476996.

・Oikawa M, Kobayashi H, Sanbo M, Mizuno N, Iwatsuki K, Takashima T, Yamauchi K, Yoshida F, Yamamoto T, Shinohara T, Nakauchi H, Kurimoto K,
Hirabayashi M, Kobayashi T.
Functional primordial germ cell-like cells from pluripotent stem cells in rats.
Science. 2022 Apr 8;376(6589):176-179. doi: 10.1126/science.abl4412. Epub 2022 Apr 7. PMID: 35389778.

・Hirano M, So Y, Tsunekawa S, Kabata M, Ohta S, Sagara H, Sankoda N, Taguchi J, Yamada Y, Ukai T, Kato M, Nakamura J, Ozawa M, Yamamoto T, Yamada Y.
MYCL-mediated reprogramming expands pancreatic insulin-producing cells.
Nat Metab. 2022 Feb;4(2):254-268. doi: 10.1038/s42255-022-00530-y. Epub 2022 Feb 10. PMID: 35145326.

2021

・Okamoto I, Nakamura T, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Nakamura SI, Ema M, Yamamoto T, Saitou M.
The X chromosome dosage compensation program during the development of cynomolgus monkeys.
Science. 2021 Nov 19;374(6570):eabd8887. doi: 10.1126/science.abd8887. Epub 2021 Nov 19. PMID: 34793202.

・Ishikura Y, Ohta H, Sato T, Murase Y, Yabuta Y, Kojima Y, Yamashiro C, Nakamura T, Yamamoto T, Ogawa T, Saitou M.
In vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells.
Cell Stem Cell. 2021 Dec 2;28(12):2167-2179.e9. doi: 10.1016/j.stem.2021.08.005. Epub 2021 Sep 7. PMID: 34496297.