[Event Report] EMBO | The Company of Biologists Workshop: Molecular mechanisms of developmental and regenerative biology
  • April 26, 2022
  • April 29, 2022

[Event Report] EMBO | The Company of Biologists Workshop: Molecular mechanisms of developmental and regenerative biology

We held the EMBO | The Company of Biologists Workshop on 26 –29 April 2022, via Zoom online. A total of 514 researchers and students (280 were registered from outside Japan) registered for the workshop, and nearly 1,200 people participated over the four days.

This EMBO Workshop will discuss cell fate decisions during the transition from pluripotency to lineage commitment in early development, the interactions of stem cells with their niches during lineage specification, and the spatiotemporal control of cell identity during the differentiation of somatic lineages and the germline. The complex multi-tissue interactions in embryoids and organoids will be discussed as experimental models for the understanding of patterning in the embryo, tissue morphogenesis and organogenesis. Mathematical modelling approaches will address how quantitative physical principles can help understand cell decision making. New insights into regenerative biology will be presented by investigating responses to tissue damage or loss and the developmental kinetics leading to aberrant phenotypes.

Official website

EMBO | The Company of Biologists Workshop
Molecular mechanisms of developmental and regenerative biology


Date & Time:
April 26 (Tue) 16:00–19:40 [JST]
April 27 (Wed) 9:00–19:55 [JST]
April 28 (Thu) 16:00–19:55 [JST]
April 29 (Fri) 16:00–20:15 [JST]
Zoom Online Meeting
- Highspeed LAN/WiFi environment advised for stability
- Update the software to the latest version


Day 1 – 26 April 2022 (Japan Time, JST)

Session 1 Control of pluripotent cell identity
Chair:Ian Chambers
16:00-16:10 Opening remarks
16:10-16:35 Keynote: Regenerative medicine using stem cells
  Shinya Yamanaka
16:35-17:00 Pluripotency and reprogramming
  Hans Scholer
17:00-17:25 Transition of pluripotency states
  Austin Smith
17:25-17:40 Selected speaker
17:40-18:10 Break (30 mins)
Session 2 Control of early developmental identity
Chair:Austin Smith
18:10-18:35 Self-organising in gastrulation
  Marta Shahbazi
18:35-19:00 Oocyte epigenome
  Azusa Inoue
19:00-19:15 Selected speaker
19:15-19:40 Multi-cellular self-organisation
  Takashi Hiiragi

Day 2 – 27 April 2022 (Japan Time, JST)

Session 3 North American session
Chair:Patrick Tam
09:00-09:25 Lineage specification during embryogenesis
  Anna-Katerina Hadjantonakis
09:25-09:40 Selected speaker
09:40-10:05 Synthetic embryology
  Jianping Fu
10:05-10:30 Tissue mechanics and patterning
  Amy Shyer
10:30-10:55 Dynamic modulation of X chromosome activity
  Jeannie Lee
Session 4 Single cell approaches
Chair:Ng Huck Hui
16:00-16:25 Molecular imperatives of gastrulation
  Patrick Tam
16:25-16:40 Selected speaker
16:40-17:05 Single cell technologies to understand organ development and regeneration
  Barbara Treutlein
17:05-17:10 Transition
17:10-18:10 Poster session 1
  Poster (60-min) Short oral talks by young researchers
18:10-18:40 Break (30-min)
Session 5 Neural development
Chair:Mitinori Saitou
18:40-19:05 Neural stem cells
  Yukiko Gotoh
19:05-19:30 "Science in Society" lecture
  Misao Fujita
19:30-19:55 Systems biology of neural organoid development
  Ng Huck-Hui

Day 3 – 28 April 2022 (Japan Time, JST)

Session 6 Regeneration I
Chair:Barbara Treutlein
16:00-16:25 Epigenetic inheritance
  Anne Ferguson-Smith
16:25-16:40 Selected speaker
16:40-17:05 YI Lecture:Symmetry and regeneration in planarian
  Jochen Rink
17:05-17:10 Transition
17:10-18:10 Poster session 2
  Poster (60-min) Short oral talks by young researchers
18:10-18:40 Break (30-min)
Session 7 Regeneration II
Chair:Elly Tanaka
18:40-19:05 Cellular plasticity
  Maximina Yun
19:05-19:30 "Women in Science" lecture
  Masayo Takahashi
19:30-19:55 Keynote: Regenerative biology of planaria
  Kiyokazu Agata

Day 4 – 29 April 2022 (Japan Time, JST)

Session 8 Physical principles and modeling
Chair:Takashi Hiiragi
16:00-16:25 Keynote Tissue mechanics and morphogenesis
  Carl-Phillip Heisenberg
16:25-16:50 Cell and tissue mechanics
  Xavier Trepat
16:50-17:05 Selected speaker
17:05-17:30 Teasing apart the impact of electric fields on single-cell motility
  Ruth Baker
17:30-18:00 Break (30-min)
Session 9 Germ cells: genetic and epigenetic inheritance
Chair:Hans Scholer
18:00-18:25 In vitro gametogenesis
  Mitinori Saitou
18:25-18:50 Axolotl regeneration
  Elly Tanaka
18:50-19:05 Selected speaker
19:05-19:30 Spermatogonial stem cells
  Shosei Yoshida
19:30-19:45 Discussion
19:45-20:00 Poster Prize Presentation
20:00-20:15 Closing remarks


  • Registration Deadline: 26 March 2022
  • Abstract Submission Deadline: 19 March 2022
  • Chosen Participants Will Be Notified By 26 March 2022
Online Application

For registration details, visit here.


  • Ian Chambers (The University of Edinburgh, UK)
  • Tadashi Ogawa (Kyoto University, JP)
  • Mitinori Saitou (Kyoto University, JP)


  • Takashi Hiiragi (Hubrecht Institute, NL)
  • Patrick Tam (Childrens Medical Research Instiute, AU)
  • Elly Tanaka (Institute of Molecular Pathology, AT)


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  • Phone: +81-75-753-9882