We held the EMBO | The Company of Biologists Workshop on 26 –29 April 2022, via Zoom online. A total of 514 researchers and students (280 were registered from outside Japan) registered for the workshop, and nearly 1,200 people participated over the four days.
This EMBO Workshop will discuss cell fate decisions during the transition from pluripotency to lineage commitment in early development, the interactions of stem cells with their niches during lineage specification, and the spatiotemporal control of cell identity during the differentiation of somatic lineages and the germline. The complex multi-tissue interactions in embryoids and organoids will be discussed as experimental models for the understanding of patterning in the embryo, tissue morphogenesis and organogenesis. Mathematical modelling approaches will address how quantitative physical principles can help understand cell decision making. New insights into regenerative biology will be presented by investigating responses to tissue damage or loss and the developmental kinetics leading to aberrant phenotypes.
Session 1 Control of pluripotent cell identity | |
Chair:Ian Chambers | |
16:00-16:10 | Opening remarks |
16:10-16:35 | Keynote: Regenerative medicine using stem cells |
Shinya Yamanaka | |
16:35-17:00 | Pluripotency and reprogramming |
Hans Scholer | |
17:00-17:25 | Transition of pluripotency states |
Austin Smith | |
17:25-17:40 | Selected speaker |
17:40-18:10 | Break (30 mins) |
Session 2 Control of early developmental identity | |
Chair:Austin Smith | |
18:10-18:35 | Self-organising in gastrulation |
Marta Shahbazi | |
18:35-19:00 | Oocyte epigenome |
Azusa Inoue | |
19:00-19:15 | Selected speaker |
19:15-19:40 | Multi-cellular self-organisation |
Takashi Hiiragi |
Session 3 North American session | |
Chair:Patrick Tam | |
09:00-09:25 | Lineage specification during embryogenesis |
Anna-Katerina Hadjantonakis | |
09:25-09:40 | Selected speaker |
09:40-10:05 | Synthetic embryology |
Jianping Fu | |
10:05-10:30 | Tissue mechanics and patterning |
Amy Shyer | |
10:30-10:55 | Dynamic modulation of X chromosome activity |
Jeannie Lee | |
Session 4 Single cell approaches | |
Chair:Ng Huck Hui | |
16:00-16:25 | Molecular imperatives of gastrulation |
Patrick Tam | |
16:25-16:40 | Selected speaker |
16:40-17:05 | Single cell technologies to understand organ development and regeneration |
Barbara Treutlein | |
17:05-17:10 | Transition |
17:10-18:10 | Poster session 1 |
Poster (60-min) Short oral talks by young researchers | |
18:10-18:40 | Break (30-min) |
Session 5 Neural development | |
Chair:Mitinori Saitou | |
18:40-19:05 | Neural stem cells |
Yukiko Gotoh | |
19:05-19:30 | "Science in Society" lecture |
Misao Fujita | |
19:30-19:55 | Systems biology of neural organoid development |
Ng Huck-Hui |
Session 6 Regeneration I | |
Chair:Barbara Treutlein | |
16:00-16:25 | Epigenetic inheritance |
Anne Ferguson-Smith | |
16:25-16:40 | Selected speaker |
16:40-17:05 | YI Lecture:Symmetry and regeneration in planarian |
Jochen Rink | |
17:05-17:10 | Transition |
17:10-18:10 | Poster session 2 |
Poster (60-min) Short oral talks by young researchers | |
18:10-18:40 | Break (30-min) |
Session 7 Regeneration II | |
Chair:Elly Tanaka | |
18:40-19:05 | Cellular plasticity |
Maximina Yun | |
19:05-19:30 | "Women in Science" lecture |
Masayo Takahashi | |
19:30-19:55 | Keynote: Regenerative biology of planaria |
Kiyokazu Agata |
Session 8 Physical principles and modeling | |
Chair:Takashi Hiiragi | |
16:00-16:25 | Keynote Tissue mechanics and morphogenesis |
Carl-Phillip Heisenberg | |
16:25-16:50 | Cell and tissue mechanics |
Xavier Trepat | |
16:50-17:05 | Selected speaker |
17:05-17:30 | Teasing apart the impact of electric fields on single-cell motility |
Ruth Baker | |
17:30-18:00 | Break (30-min) |
Session 9 Germ cells: genetic and epigenetic inheritance | |
Chair:Hans Scholer | |
18:00-18:25 | In vitro gametogenesis |
Mitinori Saitou | |
18:25-18:50 | Axolotl regeneration |
Elly Tanaka | |
18:50-19:05 | Selected speaker |
19:05-19:30 | Spermatogonial stem cells |
Shosei Yoshida | |
19:30-19:45 | Discussion |
19:45-20:00 | Poster Prize Presentation |
20:00-20:15 | Closing remarks |
For registration details, visit here.