Jinghao Chen

Mathematical modeling with computational differential equations

My primary research interests lie in the domain of computational and applied mathematics, with a strong focus on mathematical biology. Within this field, I develop mathematical models that incorporate appropriate partial differential equations (PDEs) to effectively capture and study a wide range of biological phenomena. My research endeavors are driven by a deep passion for designing and analyzing such models and developing numerical algorithms to solve the associated PDEs. Subsequently, I engage in simulations and thorough data analysis and visualization to comprehensively illuminate biological systems. Given the intricacies inherent in biophysical modeling, I am actively involved in data-driven model parameter inference, particularly in leveraging noisy qualitative data to alleviate the high precision demands often placed on experimental data by biologist collaborators.
Within this research framework, I particularly focus on the mechanosensitive ion channel, PIEZO1, which plays a pivotal role in the developmental processes and dynamic behaviors of diverse cell types. In a recent research project, I embarked on unraveling the contributions of PIEZO1 to collective migration in the context of skin wound healing, using an integrative approach involving both experimental and mathematical modeling techniques.

着任日

2024年8月1日