Research
In our genome, only 1.5% of DNA encodes for proteins and 98% is non-coding, of which function is unknown. Inoue laboratory aims to understand human regulome that underlies complex biological phenomena, such as cell differentiation, evolution, and diseases by applying cutting edge genomic/epigenomic technologies.
Pubilications 
- Whalen, S.*, Inoue, F.*, Ryu, H.*, Fair, T., Markenscoff-Papadimitriou, E., Keough, K., Kircher, M., Martin, B., Alvarado, B., Elor, O., Laboy Cintron, D., Williams, A., Hassan Samee, M.A., Thomas, S., Krencik, R., Ullian, E.M., Kriegstein, A., Rubenstein, J.L., Shendure, J., Pollen, A.A., Ahituv, N.,^ Pollard, K.S.^ (2023). Machine learning dissection of human accelerated regions in primate neurodevelopment. Neuron, 111(6), 857–873.DOI
- Kreimer, A.*^, Ashuach, T.*, Inoue, F.*, Khodaverdian, A., Deng, C., Yosef, N.^ & Ahituv, N.^ (2022). Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. Nature Communications, 13(1), 1504. DOI
- Gordon, M. G.*, Inoue, F.*^, Martin, B.*, Schubach, M.*, Agarwal, V., Whalen, S., Feng, S., Zhao, J., Ashuach, T., Ziffra, R., Kreimer, A., Georgakopoulous-Soares, I., Yosef, N., Ye, C. J., Pollard, K. S., Shendure, J.^, Kircher, M.^ & Ahituv, N.^ (2020). lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Nature Protocols, 15(8), 2387–2412. DOI
News
Recruit
We are looking for motivated grad students and postdocs!
Please feel free to contact us.
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