Kenichiro Miura
| Position | Lecturer |
|---|---|
| Group name | Isa Group |
| Research Field | Neuroscience |
| Awards | Young Investigator Award (1996), Japan Neural Network Society, Research Award (2005), Japan Neural Network Society Best Research Award (2011), Japan Neural Network Society |
| ORCID | https://orcid.org/0000-0002-3722-7837 |
| Researchmap | https://researchmap.jp/kenichiromiura?lang=en |
| Joined | 2025/04/01 |
Research Overview
To gain deeper insight into the etiology and pathophysiology of psychiatric disorders, research using appropriate animal models is indispensable, complementing clinical studies of patients. I posit that a promising avenue lies in bidirectional research utilizing translatable indices of cognitive behaviors and event-related potentials that exhibit high homology between humans and non-human primates.
At the Institute for the Advanced Study of Human Biology (ASHBi), we are actively engaged in the generation and analysis of genome-edited macaque monkey models, representing a potential frontier in novel primate models of psychiatric disorders. Within this endeavor, I am collaborating with specialists in non-human primate physiology and ethology to comprehensively delineate the phenotypes of the genome-edited models. This involves measuring and analyzing brain neuroimaging data obtained through magnetic resonance imaging, neurophysiological functions including electroencephalography, event-related potentials, and eye movements, cognitive task performance, and behaviors observed in social interaction tasks. By rigorously comparing and contrasting these findings with insights gleaned from human clinical studies, we aim to ascertain the utility of these animal models for psychiatric disorders and to expedite both forward and reverse translational research.
Biography
Kenichiro Miura has been a Junior Associate Professor at ASHBi since April 2025. He obtained his PhD from Hosei University in 1998. From 1998 to 2005, he held postdoctoral research positions at the Japan Science and Technology Agency (JST), the National Institutes of Health (NIH) in the US, and Kyoto University. He then became an Assistant Professor at Kyoto University Graduate School of Medicine from 2005 to 2019. Following that, he worked as a Section Chief at the National Center of Neurology and Psychiatry (NCNP) from 2019 to 2024 and as a researcher at the National Institute for Physiological Sciences (NIPS) from 2024 to 2025.
Publications
Miura K, Yoshida M, Morita K, Fujimoto M, Yasuda Y, Yamamori H, Takahashi J, Miyata S, Okazaki K, Matsumoto J, Toyomaki A, Makinodan M, Hashimoto N, Onitsuka T, Kasai K, Ozaki N, Hashimoto R. Gaze behaviors during free viewing revealed differences in visual salience processing across four major psychiatric disorders: a mega-analysis study of 1012 individuals. Mol Psychiatry. 30(4):1594-1600, 2025, doi: 10.1038/s41380-024-02773-5
Matsumoto J, Fukunaga M, Miura K, Nemoto K, Okada N, Hashimoto N, Morita K, Koshiyama D, Ohi K, Takahashi T, Koeda M, Yamamori H, Fujimoto M, Yasuda Y, Ito S, Yamazaki R, Hasegawa N, Narita H, Yokoyama S, Mishima R, Miyata J, Kobayashi Y, Sasabayashi D, Harada K, Yamamoto M, Hirano Y, Itahashi T, Nakataki M, Hashimoto RI, Tha KK, Koike S, Matsubara T, Okada G, Yoshimura R, Abe O, van Erp TGM, Turner JA, Jahanshad N, Thompson PM, Onitsuka T, Watanabe Y, Matsuo K, Yamasue H, Okamoto Y, Suzuki M, Ozaki N, Kasai K, Hashimoto R, Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals, Mol Psychiatry, 28(11):4915-4923, 2023, doi: 10.1038/s41380-023-02224-7
Okazaki K, Miura K, Matsumoto J, Hasegawa N, Fujimoto M, Yamamori H, Yasuda Y, Makinodan M, Hashimoto R, Discrimination in the clinical diagnosis between patients with schizophrenia and healthy controls using eye movement and cognitive functions., Psychiatry Clin Neurosci, 77(7): 393-400, 2023, doi: 10.1111/pcn.13553
Korai Y, Miura K, A dynamical model of visual motion processing for arbitrary stimuli including type II plaids., Neural Netw, 162: 46-68, 2023, doi: 10.1016/j.neunet.2023.02.039
Miura K, Inaba N, Aoki Y, Kawano K, Difference in visual motion representation between cortical areas MT and MST during ocular following responses, J Neurosci, 34(6): 2160-2168, 2014
Shaikh AG, Miura K, Optican LM, Ramat S, Leigh RJ, Zee DS, A new familial disease of saccadic oscillations and limb tremor provides clues to mechanisms of common tremor disorders, Brain, 130: 3020-3031, 2007, doi:110.1093/brain/awm240