Dr. Thales Papagiannakopoulos from New York University Grossman School of Medicine

2025年4月23日にNew York University Grossman School of Mediciney よりThales Papagiannakopoulos博士をお招きし、ASHBi Seminarを開催します。

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プログラム

タイトル

Mechanisms of Disease Progression in Cancer

Thales Papagiannakopoulos, Ph.D.
Associate Professor, Department of Pathology, Perlmutter Cancer Center, NYU School of Medicine, New York, NY
Director, Molecular Oncology and Tumor Immunology Training Program, NYU School of Medicine, New York, NY

Biography

Thales Papagiannakopoulos obtained his Ph.D. in Molecular, Cellular and Developmental Biology in Dr. Ken Kosik’s lab at UC Santa Barbara (2005-2010). His research focused on uncovering the role of microRNAs in regulating embryonic stem cell pluripotency and cancer. In 2010, he started his postdoctoral studies in Dr. Tyler Jacks’ laboratory at MIT where he studied the molecular mechanisms that contribute to cancer at an organismal level, using autochthonous mouse models of cancer. He pioneered the use of novel CRISPR/Cas9-based genome engineering in pre-clinical lung cancer mouse models.

Thales joined NYU School of Medicine in 2015 as faculty in the Department of Pathology and has since been promoted to associate Professor and is also the Director of the Molecular Oncology and Tumor Immunology Program. Using both mouse and human pre-clinical models, his lab has developed a platform to rapidly characterize the function of clinically relevant lung cancer mutations, elucidate their mechanism of action and identify novel targeted therapies against complex genetic subtypes of lung cancer. Thales’ group has made significant progress in characterizing and identifying novel therapies against the most aggressive genetic subsets of lung cancer with KEAP1 and LKB1 mutations. These findings are of great importance given that patients with these mutations have the worst prognosis of all lung cancer patients and do not respond to standard of care. Finally, his group is investigating how the major genetic subsets of lung cancer differentially impact systemic physiology.

参加登録

要事前登録

対象者

京都大学に所属する研究者、及び、学生

ホスト

村川　泰裕（京都大学高等研究院 ヒト生物学高等研究拠点（ASHBi） PI / 教授）

お問い合わせ

京都大学高等研究院　ヒト生物学高等研究拠点（WPI-ASHBi）
ashbi-event [at] mail2.adm.kyoto-u.ac.jp
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