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[Event Report] EMBO | The Company of Biologists Workshop: Molecular mechanisms of developmental and regenerative biology

We held the EMBO | The Company of Biologists Workshop on 26 –29 April 2022, via Zoom online. A total of 514 researchers and students (280 were registered from outside Japan) registered for the workshop, and nearly 1,200 people participated over the four days.

This EMBO Workshop will discuss cell fate decisions during the transition from pluripotency to lineage commitment in early development, the interactions of stem cells with their niches during lineage specification, and the spatiotemporal control of cell identity during the differentiation of somatic lineages and the germline. The complex multi-tissue interactions in embryoids and organoids will be discussed as experimental models for the understanding of patterning in the embryo, tissue morphogenesis and organogenesis. Mathematical modelling approaches will address how quantitative physical principles can help understand cell decision making. New insights into regenerative biology will be presented by investigating responses to tissue damage or loss and the developmental kinetics leading to aberrant phenotypes.

Official website

EMBO | The Company of Biologists Workshop
Molecular mechanisms of developmental and regenerative biology

Program

Date

26 April 2022 – 29 April 2022

Time

April 26 (Tue) 16:00–19:40 [JST]
April 27 (Wed) 9:00–19:55 [JST]
April 28 (Thu) 16:00–19:55 [JST]
April 29 (Fri) 16:00–20:15 [JST]

Venue

Zoom Online Meeting
[NOTE]
– Highspeed LAN/WiFi environment advised for stability
– Update the software to the latest version

Language

English

Fee

Free

Schedule

Day 1 – 26 April 2022 (Japan Time, JST)

Session 1 Control of pluripotent cell identity
Chair:Ian Chambers

16:00-16:10Opening remarks
16:10-16:35Keynote: Regenerative medicine using stem cells
Shinya Yamanaka
16:35-17:00Pluripotency and reprogramming
Hans Scholer
17:00-17:25Transition of pluripotency states
Austin Smith
17:25-17:40Selected speaker
17:40-18:10Break (30 mins)

Session 2 Control of early developmental identity
Chair:Austin Smith

18:10-18:35Self-organising in gastrulation
Marta Shahbazi
18:35-19:00Oocyte epigenome
Azusa Inoue
19:00-19:15Selected speaker
19:15-19:40Multi-cellular self-organisation
Takashi Hiiragi

Day 2 – 27 April 2022 (Japan Time, JST)

Session 3 North American session
Chair:Patrick Tam

09:00-09:25Lineage specification during embryogenesis
Anna-Katerina Hadjantonakis
09:25-09:40Selected speaker
09:40-10:05Synthetic embryology
Jianping Fu
10:05-10:30Tissue mechanics and patterning
Amy Shyer
10:30-10:55Dynamic modulation of X chromosome activity
Jeannie Lee

Session 4 Single cell approaches
Chair:Ng Huck Hui

16:00-16:25Molecular imperatives of gastrulation
Patrick Tam
16:25-16:40Selected speaker
16:40-17:05Single cell technologies to understand organ development and regeneration
Barbara Treutlein
17:05-17:10Transition
17:10-18:10Poster session 1
Poster (60-min) Short oral talks by young researchers
18:10-18:40Break (30-min)

Session 5 Neural development
Chair:Mitinori Saitou

18:40-19:05Neural stem cells
Yukiko Gotoh
19:05-19:30“Science in Society” lecture
Misao Fujita
19:30-19:55Systems biology of neural organoid development
Ng Huck-Hui

Day 3 – 28 April 2022 (Japan Time, JST)

Session 6 Regeneration I
Chair:Barbara Treutlein

16:00-16:25Epigenetic inheritance
Anne Ferguson-Smith
16:25-16:40Selected speaker
16:40-17:05YI Lecture:Symmetry and regeneration in planarian
Jochen Rink
17:05-17:10Transition
17:10-18:10Poster session 2
Poster (60-min) Short oral talks by young researchers
18:10-18:40Break (30-min)

Session 7 Regeneration II
Chair:Elly Tanaka

18:40-19:05Cellular plasticity
Maximina Yun
19:05-19:30“Women in Science” lecture
Masayo Takahashi
19:30-19:55Keynote: Regenerative biology of planaria
Kiyokazu Agata

Day 4 – 29 April 2022 (Japan Time, JST)

Session 8 Physical principles and modeling
Chair:Takashi Hiiragi

16:00-16:25Keynote Tissue mechanics and morphogenesis
Carl-Phillip Heisenberg
16:25-16:50Cell and tissue mechanics
Xavier Trepat
16:50-17:05Selected speaker
17:05-17:30Teasing apart the impact of electric fields on single-cell motility
Ruth Baker
17:30-18:00Break (30-min)

Session 9 Germ cells: genetic and epigenetic inheritance
Chair:Hans Scholer

18:00-18:25In vitro gametogenesis
Mitinori Saitou
18:25-18:50Axolotl regeneration
Elly Tanaka
18:50-19:05Selected speaker
19:05-19:30Spermatogonial stem cells
Shosei Yoshida
19:30-19:45Discussion
19:45-20:00Poster Prize Presentation
20:00-20:15Closing remarks

Registration

  • Registration Deadline: 26 March 2022
  • Abstract Submission Deadline: 19 March 2022
  • Chosen Participants Will Be Notified By 26 March 2022

Online Application

For registration details, visit here.

Hosts

Co-Hosts

  • Takashi Hiiragi (Hubrecht Institute, NL)
  • Patrick Tam (Childrens Medical Research Instiute, AU)
  • Elly Tanaka (Institute of Molecular Pathology, AT)

Contact

ASHBi Office

  • ashbi-symposium[*]mail2.adm.kyoto-u.ac.jp
    Please change [*] to @.
  • Phone: +81-75-753-9882