From Human Genome to Innovative Medicine

ResearchResearch

The rapid evolution of genome sequencing technology has led to a better understanding of various types of human diseases. The ultimate goal of the genomic analysis is to free people from disease. We are conducting research to gain a deeper understanding of the basic mechanisms of the human genome, the blueprint of life that is full of unknowns, with the aim of bringing innovation to drug discovery, medicine and healthcare in the future.

Research

Pubilications Publications

  • Oguchi A, Suzuki A, Komatsu S, Yoshitomi H, Bhagat S, Son R, Bonnal RJP, Kojima S, Koido M, Takeuchi K, Myouzen K, Inoue G, Hirai T, Sano H, Takegami Y, Kanemaru A, Yamaguchi I, Ishikawa Y, Tanaka N, Hirabayashi S, Konishi R, Sekito S, Inoue T, Kere J, Takeda S, Takaori-Kondo A, Endo I, Kawaoka S, Kawaji H, Ishigaki K, Ueno H, Hayashizaki Y, Pagani M, Carninci P, Yanagita M; ITEC Consortium; Parrish N, Terao C, Yamamoto K, Murakawa Y. An atlas of transcribed enhancers across helper T cell diversity for decoding human diseases. Science. 385(6704):eadd8394. (2024)
  • Hirabayashi S, Bhagat S., Matsuki Y, Takegami Y, Uehata T, Kanemaru A, Itoh M, Shirakawa K, Takaori-Kondo A, Takeuchi O, Carninci P, Katayama S, Hayashizaki Y, Kere J, Kawaji H, Murakawa Y. NET-CAGE Characterizes Dynamics and Topology of Human Transcribed Cis-regulatory Elements. Nature Genetics 51, 1369-1379 (2019)
  • Rybak-Wolf A (#), Jens M (#), Murakawa Y (#), Herzog M, Landthaler M, Rajewsky N. A variety of Dicer substrates in human and C.elegans. Cell 159, 1153-1167 (2014) (#co-first authors)

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Our research group is looking for research staff, graduate students (doctoral and master's programs at the Graduate School of Medicine Kyoto University), and undergraduate students. We welcome people with enthusiasm. If you are interested, please contact us from " Contact ". We also accept lab tours at any time. Please refer to the following link for application guidelines and other information